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Empirical Modeling for Oxygen Transport Processes and Related Physiological and Bioprocess Systems

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Oxygen Transport to Tissue XVII

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 388))

Abstract

Engineering analysis is based upon quantification of systems via mathematical modeling and computer simulation. The most fundamental approach is to begin with the basic principles of physics, chemistry and biology and formulate phenomenological models that are based upon mass, energy and momentum balances. This procedure evolves equations with specific system parameters such as, diffusivity, velocity, rate constants, etc., that can be examined to determine system sensitivity to various inputs. The theoretical modeling approach has many advantages because it yields a primary understanding of system behavior at the process parameter level.

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References

  1. Lees, D., and Hougen, J., Journal of Industrial & Engineering Chemistry 48, 1064–1068.

    Google Scholar 

  2. Lewis, CL, Bruley, D.F., and Hunt, D.H., 1967, Evaluation of temperature pulse characteristics and pulse testing for thermal dynamic analysis. I&EC Process Des. Dev. 6:281–286.

    Article  CAS  Google Scholar 

  3. Luyben, W.L., 1990 Process Modeling, Simulation and Control for Chemical Engineers, 2nd Edition. New York: McGraw-Hill.

    Google Scholar 

  4. Clements, W.C., Jr., and Schnelle, K.B., 1963. Pulse testing for dynamic analysis. I&EC Process Des. Dev. 2(2):94–102.

    Article  CAS  Google Scholar 

  5. Bruley, D.F., and Prados, J.W., 1964, The frequency response analysis of a wetted wall adiabatic humidifier. AIChEJ. 10:612–616.

    Article  Google Scholar 

  6. Kang, K.A., Bruley, D.F., Londono, J.M., and Chance, B., 1994, Highly Scattering Optical System Identification via frequency Response Analysis of NIR-TRS Spectra, Annuals of Biomedical Engineering. Vol. 22:240–252.

    Article  CAS  Google Scholar 

  7. Coughanowr, D.R., 1991, Process systems analysis and control. New York, McGraw-Hill.

    Google Scholar 

  8. Filon, L.N.G. 1928, On a quadrature formula for trigonometric integrals., Proc. Roy. Soc. Edinburgh. 49:38–47.

    Google Scholar 

  9. Bruley, D.F., 1975, Filon’s Method Data Reduction Code. Unpublished.

    Google Scholar 

  10. Dalton, J.C., Gupta, S., Bruley, M.D., Kang, K.A., and Bruley, D.F., Liquid Chromatographic Process Identification via Pulse Testing for Column Standardization and Scale-Up, Submitted to the Journal of Chromatography.

    Google Scholar 

  11. Bruley, D.F., Bicher, H.I., Reneau, D.D., and Knisely, M.H., 1971, Auto-regulatory Phenomena Related to Cerebral Tissue Oxygenation, Advances in Bioengineering. CEP Symposium Series. 114, Vol. 67, 195–201.

    Google Scholar 

  12. Bruley, D.F., Reneau, D.D., Bicher, H.I. and Knisely, M.H., September 1973, Studies of Cerebral Tissue Oxygenation and Related Autoregulation, Advances in Chemistry Series, Chemical Engineering in Medicine. 118, 290–302.

    Article  Google Scholar 

  13. Bicher, H.I., Reneau, D.D., Bruley, D.F., and Knisely, M.H., 1972, Autoregulation of Oxygen Supply to Microareas of Brain Tissue Under Hypoxic and Hyperbaric Conditions, VIIth International Meeting, European Society for Microcirculation. Published by S. Karger. 529–531.

    Google Scholar 

  14. Bruley, D.F., Bicher, H.I., Reneau, D.D. and Knisely, M.H., 1973, Autoregulation of Chemotransport to Brain Tissue, Regulation and Control in Physiological Systems Symposium Proceedings, Rochester, New York, 501.

    Google Scholar 

  15. Bruley, D.F. and Hunt, D.H. 1974, Theoretical Studies of Brain Autoregulation; Oxygen Transport to Tissue, Microvascular Research, Vol. 8, 314–319.

    Article  PubMed  CAS  Google Scholar 

  16. Bruley, D.F., Bicher, H.I., Hunt, D.H., and Flache, W.E., 1975, Autoregulatory Mechanisms Controlling the Supply of Oxygen to Microareas of Brain Tissue, Biochemistry and Experimental Biology, Vol. XI -N. 2, 1255–161.

    Google Scholar 

  17. Bicher, H.I., Hunt, D.H., and Bruley, D.F., 1976, Automatic and Pharmacological Control of Oxygen Autoregulation Mechanisms in Brain Tissue, Oxygen Transport to Tissue - II; Plenum Publishing Corporation, Editors, J. Grote, D. Reneau and G. Thews, 383–389.

    Google Scholar 

  18. Kang, K.A., Bruley, D.F., Londono, J. Chance, B., Frequency response by pulse reduction for the analysis of TRS spectra. Proc. ISOTTXVI. In: Hogan, M.C., Mathieu-Costello, O., Polle, D.C., Wagner, P.D., eds. Advances in experimental medicine and biology. New York: Plenum Press, (in press).

    Google Scholar 

  19. Kang, K.A., Bruley, D.F., Kitai, T., and Chance, B., System Parameter Analysis of NIR-TRS Spectra from Homogeneous Media with and without an Absorbing Boundary and Heterogeneous Media with a single Absorber (this volume).

    Google Scholar 

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© 1996 Plenum Press, New York

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Bruley, D.F. (1996). Empirical Modeling for Oxygen Transport Processes and Related Physiological and Bioprocess Systems. In: Ince, C., Kesecioglu, J., Telci, L., Akpir, K. (eds) Oxygen Transport to Tissue XVII. Advances in Experimental Medicine and Biology, vol 388. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0333-6_13

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  • DOI: https://doi.org/10.1007/978-1-4613-0333-6_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-8002-3

  • Online ISBN: 978-1-4613-0333-6

  • eBook Packages: Springer Book Archive

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