Abstract
The presence or absence of specific cell surface receptors can influence the host range and tissue tropism of viruses. For example, receptors for poliovirus are known to confer susceptibility on human and some primate cells, while cells of other species lack receptors and are resistant to infection [1]. Although postattachment restrictions are known, virtually all viruses appear to be restricted initially by appropriate receptor expression on the target cells. The most intensively studied viral receptors have been those for the picornaviruses, myxoviruses, and retroviruses. For these, detailed information on the mechanisms of attachment and penetration have been reported [2]. Even the chromosomal locations of the structural genes for some of these receptors are known and have been assigned to human chromosome 19 [3].
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McClintock, P.R., Notkins, A.L. (1984). Viral Receptors: Expression, Regulation and Relationship to Infectivity. In: Notkins, A.L., Oldstone, M.B.A. (eds) Concepts in Viral Pathogenesis. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5250-4_14
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DOI: https://doi.org/10.1007/978-1-4612-5250-4_14
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