Abstract
One of the most noteworthy features of the behavior of human drug abusers is the extent to which their behavioral repertoire consists of responses maintained by procurement, preparation, and the ultimate administration of drug. Since abusers can be totally consumed with drug-seeking and drug-oriented behaviors and since drug abuse is obviously maladaptive, many theories of drug addiction and abuse have emphasized what were thought to be fundamental pathologies in personality or motivations unique to the drug abuser. However, as Sidman (1960) noted many years ago, pathological states in behavior, as in medicine, can be manifestations of normal processes which are determined, lawful extensions of normal functioning in what is often an atypical environment. Excessive behavior maintained by drug, therefore, may be functionally no different from other behavior but maintained in an environment that promotes its predominance. Following the above interpretation, laboratory studies can examine the extent to which drug-seeking or drug-taking behavior is different from behavior maintained by other stimulus events. A related question is whether the reinforcing effects of drugs are fundamentally different from the reinforcing effects of other events that maintain behavior.
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References
Barrett, J. E., Katz, J. L., & Glowa, J. R. (1981). Effects of d-amphetamine on responding of squirrel monkeys maintained under second-order schedules of food presentation, electric shock presentation or stimulus-shock termination. Journal of Pharmacology and Experimental Therapeutics, 218, 692–700.
Goldberg, S. R. (1973). Comparable behavior maintained under fixed-ratio and second-order schedules of food presentation, cocaine injection or d-amphetamine injection in the squirrel monkey. Journal of Pharmacology and Experimental Therapeutics, 186, 18–30.
Goldberg, S. R., & Gardner, M. L. (1981). Second-order schedules: Extended sequences of behavior controlled by brief environmental stimuli associated with drug self-administration. In T. Thompson & C. E. Johanson (Eds.), Behavioral pharmacology of human drug dependence (National Institute on Drug Abuse Research Monograph 37, pp. 241–270). Washington, DC: U.S. Government Printing Office.
Goldberg, S. R., & Kelleher, R. T. (1976). Behavior controlled by scheduled injections of cocaine in squirrel and rhesus monkeys. Journal of the Experimental Analysis of Behavior, 25, 93–104.
Goldberg, S. R., Kelleher, R. T., & Goldberg, D. M. (1981a). Fixed ratio responding under second-order schedules of food presentation or cocaine injection. Journal of Pharmacology and Experimental Therapeutics, 218, 271–281.
Goldberg, S. R., & Spealman, R. D. (1982). Maintenance and suppression of behavior by nicotine injections in squirrel monkeys. Federation Proceedings, 41, 21 6–220.
Goldberg, S. R., Spealman, R. D., & Goldberg, D. M. (1981b). Persistent highrate behavior maintained by intravenous self-administration of nicotine. Science, 214, 573–575.
Goldberg, S. R., Spealman, R. D., & Kelleher, R. T. (1979). Enhancement of drug-seeking behavior by environmental stimuli associated with cocaine or morphine injections. Neuropharmacology, 18, 1015–1017.
Goldberg, S. R., & Tang, A. (1977). Behavior maintained under second-order schedules of intravenous morphine injection in squirrel and rhesus monkeys. Psychopharmaco1ogy, 51, 235–242.
Gollub, L. R. (1977). Conditioned reinforcement: Schedule effects. In W. K. Honig & J. E. R. Staddon (Eds.), Handbook of operant behavior (pp. 288–312). Englewood Cliffs, NJ: Prentice-Hall.
Griffiths, R. R., Brady, J. V., & Bradford, L. D. (1979). Predicting the abuse liability of drugs with animal drug self-administration procedures: Psychomotor stimulants and hallucinogens. In T. Thompson & P. B. Dews (Eds.), Advances in behavioral pharmacology (Vol. 2, pp. 163–208). New York: Academic Press.
Henningfield, J. E., & Goldberg, S. R. (1983). Nicotine as a reinforcer in human subjects and laboratory animals. Pharmacology Biochemistry & Behavior, 19, 989–992.
Hill, R. T. (1970). Facilitation of conditioned reinforcement as a mechanism of psychomotor stimulation. In E. Costa & S. Garattini (Eds.), Amphetamines and related compounds (pp. 781–795). New York: Raven Press.
Katz, J. L. (1979). A comparison of responding maintained under second-order schedules of intramuscular cocaine injection or food presentation in squirrel monkeys. Journal of the Experimental Analysis of Behavior, 32, 419–431.
Kelleher, R. T. (1958). Fixed-ratio schedules of conditioned reinforcement with chimpanzees. Journal of the Experimental Analysis of Behavior, 1, 281–289.
Kelleher, R. T. (1966). Chaining and conditioned reinforcement. In W. K. Honig (Ed.), Operant behavior: Areas of research and application (pp. 160–212). New York: Appleton-Century-Crofts.
Kelleher, R. T. (1975). Characteristics of behavior controlled by scheduled injections of drugs. Pharmacological Reviews, 27, 307–323.
Kelleher, R. T., & Goldberg, S. R. (1977). Fixed-interval responding under second-order schedules of food presentation or cocaine injection. Journal of the Experimental Analysis of Behavior, 28, 14–2
Kelleher, R. T., & Morse, W. H. (1968). Determinants of the specificity of behavioral effects of drugs. Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie, 60, 1–56.
Morse, W. H. (1975). Introduction: The control of behavior by consequent drug injections. Pharmacological Reviews, 27, 301–305.
Pickens, R., & Thompson, T. (1968). Cocaine-reinforced behavior in rats: Effects of reinforcement magnitude and fixed-ratio size. Journal of Pharmacology and Experimental Therapeutics, 161, 122–129.
Robbins, T. W. (1975). The potentiation of conditioned reinforcement by psychomotor stimulant drugs: A test of Hill’s hypothesis. Psychopharmaco1ogia, 45, 103–114.
Sidman, M. (1960). Normal sources of pathological behavior. Science, 132, 61–68.
Sidman, M., & Stebbins, W. C. (1954). Satiation effects under fixed-ratio schedules of reinforcement. Journal of Comparative and Physiological Psychology, 47, 114–116.
Smith, R. F., Gustavson, C. R., & Gregor, G. L. (1972). Incompatibility between the pigeon’s unconditioned response to shock and the conditioned key-peck response. Journal of the Experimental Analysis of Behavior, 18, 147–153.
Spealman, R. D., & Goldberg, S. R. (1978). Drug self-administration by laboratory animals: Control by schedules of reinforcement. Annual Review of Pharmacology and Toxicology, 18, 313–339.
Spealman, R. D., & Kelleher, R. T. (1979). Behavioral effects of self-administered cocaine: Responding maintained alternately by cocaine and electric shock in squirrel monkeys. Journal of Pharmacology and Experimental Therapeutics, 210, 206–214.
Valentine, J. O., Katz, J. L., Kandel, D. A., & Barrett, J. E. (1983). Effects of cocaine, chlordiazepoxide, and chlorpromazine on responding of squirrel monkeys under second-order schedules of IM cocaine injection or food presentation. Psychopharmaco1ogy, 81, 164–169.
Woods, J. H., & Schuster, C. R. (1971). Opiates as reinforcing stimuli. In T. Thompson & R. Pickens (Eds.), Stimulus properties of drugs (pp. 163–175). New York: Appleton-Century-Crofts.
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© 1987 Springer-Verlag New York Inc.
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Katz, J.L., Goldberg, S.R. (1987). Second-Order Schedules of Drug Injection. In: Bozarth, M.A. (eds) Methods of Assessing the Reinforcing Properties of Abused Drugs. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4812-5_5
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DOI: https://doi.org/10.1007/978-1-4612-4812-5_5
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