The purpose of this work was to study possible mechanisms of radiation-induced bystander effect proceeding from its modification using different radioprotective substances: melanin, melatonin and α -tocopherol. All substances were able to statistically significant decrease the damaging effect of bystander factor from irradiated cells on non-irradiated. The protective effect against bystander irradiation was much less than against direct irradiation. Melatonin showed the best protective effect against both direct and bystander irradiations, and vitamin E – the least. According to the results, bystander factor may have physical component and oxidative nature.
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Marozik, P., Mosse, I., Mothersill, C., Seymour, C. (2007). Protection by Chemicals against Radiation-Induced Bystander Effects. In: Mothersill, C., Mosse, I., Seymour, C. (eds) Multiple Stressors: A Challenge for the Future. NATO Science for Peace and Security Series. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6335-0_16
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