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Molecularly Imprinted Polymers

  • Conference paper
Biomaterials

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 553))

Abstract

Molecularly imprinted polymers (MIPs)1–4 are highly stable polymeric molds that possess selective molecular recognition properties for various kinds of molecules. MIPs consist of highly crosslinked polymers that are synthesized in the presence of a template (imprint) molecule. After removal of template, a cavity is left, which retains affinity and selectivity for the template. Some of MIPs (such as antibody mimics), under optimized conditions, have high selectivities and afffiinity constants comparable with naturally occuring recognition systems such as monoclonal antibodies and receptors2. In addition, their unique stability is superior to that demonstrated by natural biomolecules; and they are robust and inexpensive. The simplicity of their preparation and the ease of adaptation to different practical applications make them very useful for chemical, pharmaceutical, and biotechnological industries.

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Authors and Affiliations

  1. Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University, Sihhiye, 06100, Ankara, Turkey

    Kezban Ulubayram

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  1. Kezban Ulubayram
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Editors and Affiliations

  1. Biomaterials Research Labs, Middle East Technical University, Ankara, Turkey

    Nesrin Hasirci  & Vasif Hasirci  & 

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Ulubayram, K. (2004). Molecularly Imprinted Polymers. In: Hasirci, N., Hasirci, V. (eds) Biomaterials. Advances in Experimental Medicine and Biology, vol 553. Springer, Boston, MA. https://doi.org/10.1007/978-0-306-48584-8_10

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  • DOI: https://doi.org/10.1007/978-0-306-48584-8_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0988-9

  • Online ISBN: 978-0-306-48584-8

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