Skip to main content

A Classification-Tree Hybrid Method for Studying Prognostic Models in Intensive Care

  • Conference paper
  • First Online:
Artificial Intelligence in Medicine (AIME 2001)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 2101))

Included in the following conference series:

  • 1075 Accesses

Abstract

Health care effectiveness and efficiency are under constant scrutiny especially when treatment is quite costly as in Intensive Care (IC). At the heart of quality of care programs lie prognostic models whose predictions for a particular patient population may be used as a norm to which actual outcomes of that population can be compared. This paper motivates and suggests a method based on Machine Learning and Statistical ideas to study the behavior of current IC prognostic models for predicting in-hospital mortality. An application of this method to an exemplary logistic regression model developed on the IC data from the National Intensive Care Evaluation registry reveals the model’s weaknesses and suggests ways for developing improved prognostic models.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Abu-Hanna A, Lucas PJF. Prognostic Models in Medicine AI and Statistical Approaches, (Abu-Hanna A. and Lucas PJF, eds.). Special issue of Methods of Information in Medicine 2001, 40:1–5.

    Google Scholar 

  2. Bennett D, Bion J. ABC of Intensive Care. Organisation of Intensive Care. BMJ 1999; 318:1468–1470.

    Google Scholar 

  3. Cleveland, W. S. (1979) Robust Locally Weighted Regression and Smoothing Scatterplots. J. Amer. Statist. Assoc. 74, 829–836.

    Article  MATH  MathSciNet  Google Scholar 

  4. Hand DJ. Construction and Assessment of Classification Rules. Chichester: John Wiley and Sons, 1997.

    MATH  Google Scholar 

  5. Hosmer D.W., Lemeshow S. Applied Logistic Regression, Wiley, New-York, 1989.

    Google Scholar 

  6. Hosmer D.W., Hosmer T., Le Cessie S., Lemeshow S. A Comparison of Goodness-of-fit Tests for the Logistic Regression Model. Statistics in Medicine 1997; 16:965–980.

    Article  Google Scholar 

  7. de Keizer N. An Infrastructure for Quality Assessment in Intensive Care; Prognostic Models and Terminological Systems. PhD Thesis, 2000, University of Amsterdam.

    Google Scholar 

  8. Knaus W, Draper E, Wagner D, Zimmerman J. APACHE II: a Severity of Disease Classification System. Crit Care Med 1985; 13:818–829.

    Article  Google Scholar 

  9. Kohavi R. Scaling Up the Accuracy of Naive-Bayes Classifiers: a Decision-Tree Hybrid. Proc. of the Second Int. Conference on Knowledge Discovery and Data Mining. 1996; 202–207.

    Google Scholar 

  10. Le Gall J, Lemeshow S, Saulnier F. A New Simplified Acute Physiology Score (SAPS-II) Based on a European/North American Multicenter Study. JAMA 1993; 270:2957–2963.

    Article  Google Scholar 

  11. Long WJ. A Comparison of Logistic Regression to Decision-Tree Induction in a Medical Domain. Compt Bio Res 1993:74–97.

    Google Scholar 

  12. Lucas PJF, Abu-Hanna A. Prognostic Methods in Medicine (Lucas PJF and Abu-Hanna A. eds.). Special issue of Artificial Intelligence in Medicine. 1999; 15(2):105–119.

    Google Scholar 

  13. Miller M.E., Hui S.L. Validation Techniques for Logistic Regression Models. Statistics in Medicine, 1991, Vol 10, pp. 1213–1226.

    Article  Google Scholar 

  14. Rowan K, Kerr J, Major E, McPherson K, Short A, Vessey M. Intensive Care Society’s APACHE II study in Britain and Ireland-II. BMJ 1993; 307:977–981.

    Article  Google Scholar 

  15. Schwarzer G, Vach W, Schumacher M. On Misuses of Artificial Neural Networks for Prognostic and Diagnostic Classification in Oncology. Statistics in Medicine 2000; 19: 541–561.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Abu-Hanna, A., de Keizer, N. (2001). A Classification-Tree Hybrid Method for Studying Prognostic Models in Intensive Care. In: Quaglini, S., Barahona, P., Andreassen, S. (eds) Artificial Intelligence in Medicine. AIME 2001. Lecture Notes in Computer Science(), vol 2101. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-48229-6_13

Download citation

  • DOI: https://doi.org/10.1007/3-540-48229-6_13

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42294-5

  • Online ISBN: 978-3-540-48229-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics