Conclusion
The presence of correlations between the in vivo rates of protein synthesis and relevant clinical parameters suggests that determination of the ongoing metabolic activity in immune competent cells reflects changes in the functional activity of the immune system, being of importance for the severity and time course of the critical illness. Our results encourage future studies, in order to characterize the alterations in the in vivo metabolic activity in immune competent cells in later phases of the ICU stay, characterized by a general anti-inflammatory activity and decreased resistance to opportunistic infections.
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Januszkiewicz, A., Rooyackers, O., Wernerman, J. (2006). Quantitative in vivo Protein Synthesis as a Measure of Immune Function. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 2006. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-33396-7_6
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