11.7 Conclusion
Collecting duct carcinoma is an aggressive subtype of RCC derived from the renal medulla. The tumor occurs in a wide age range, predominately in men. The usual histologic pattern is that of a tubular or tubulopapillary carcinoma with a desmoplastic stroma. Imaging features suggestive of this diagnosis include a medullary origin and an infiltrative growth pattern. This type of cancer is associated with an extremely poor prognosis. At presentation CDC is metastatic to regional lymph nodes. The characteristic location, typical histologic and radiologic appearance, and reportedly poor prognosis differentiate CDC from the more common RCC. Death usually occurs within 2 years. Various treatments have been proposed but with disappointing results, including radiation therapy, immunotherapy and some combinations of chemotherapy.
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References
Aita K, Tanimoto A, Fujimoto Y et al. (2003) Sarcomatoid collecting duct carcinoma arising in the hemodialysis-associated acquired cystic kidney: an autopsy report. Pathol Int 53:463–467
Antonelli A, Portesi E, Cozzoli A et al. (2003) The collecting duct carcinoma of the kidney: a cytogenetical study. Eur Urol 43:680–685
Auguet T, Molina JC, Lorenzo A et al. (2000) Synchronus renal cell carcinoma and Bellini duct carcinoma: a case report on a rare coincidence. World J Urol 18:449–451
Bostwick DG, Eble JN (1999) Diagnosis and classification of renal cell carcinoma. Urol Clin North Am 26:627–635
Cromie WJ, Davis CJ, DeTure FA (1979) Atypical carcinoma of kidney: possibly originating from collecting duct epithelium. Urology 13:315–317
Davis CJ, Mostofi FK, Sesterhenn IA (1995) Renal medullary carcinoma: the seventh sickle cell nephropathy. Am J Surg Pathol 19:1–11
Fleming S, Lewi HJ (1986) Collecting duct carcinoma of the kidney. Histopathology 10:1131–1141
Fukunaga M (1999) Sarcomatoid collecting duct carcinoma. Arch Pathol Lab Med 123:338–341
Fukuya T, Honda H, Goto K et al. (1996) Computed tomographic findings of Bellini duct carcinoma of the kidney. J Comput Assist Tomogr 20:399–403
Gallob JA, Upton MP, DeWolf WC et al. (2001) Long-term remission in a patient with metastatic collecting duct carcinoma treated with taxol/carboplatin and surgery. Urology 58:1058i–1058iii
Gong Y, Sun X, Haines GK et al. (2003) Renal cell carcinoma, chromophobe type, with collecting duct carcinoma and sarcomatoid components. Arch Pathol Lab Med 27:e38–e40
Kirkali Z, Celebi I, Akan G et al. (1996) Bellini duct (collecting duct) carcinoma of the kidney. Urology 47:921–923
Kuroda N, Toi M, Hirol M et al. (2002) Review of collecting duct carcinoma with focus on clinical and pathobiological aspects. Histol Histopathol 17:1329–1334
Levine E, King BF (2000) Adult malignant renal parenchymal neoplasms. In: Pollack HM, McClennan BL (eds) Clinical urology. Saunders, Philadelphia, pp 1440–1559
MacLennan GT, Farrow GM, Bostowick DG (1997) Low-grade collecting duct carcinoma of the kidney: report of 13 cases of low-grade mucinous tubulocystic renal carcinoma of possible collecting duct origin. Urology 50:679–684
Mancilla-Jimenez R, Stanley RJ, Blath RA (1976) Papillary renal cell carcinoma: a clinical, radiologic, and pathologic study of 34 cases. Cancer 38:2469–2480
Matsumoto H, Wada T, Aoki A et al. (2001) Collecting duct carcinoma with long survival treated by partial nephrectomy. Int J Urol 8:401–403
Mejean A, Roupret M, Larousserie F et al. (2003) Is there a place for radical nephrectomy in the presence of metastatic collecting duct (Bellini) carcinoma? J Urol 169:1287–1290
Milowski MI, Rosmarin A, Tickoo SK et al. (2002) Active chemotherapy for collecting duct carcinoma of the kidney. A case report and review of the literature. Cancer 94:111–116
Natsume O, Seiichiro O, Futami T et al. (1997) Bellini duct carcinoma: a case report. Jpn J Clin Oncol 27:107–110
Nguyen GK, Schumann GB (1997) Cytopathology of renal collecting duct in urine sediment. Diagn Cytopathol 16:446–449
Peyromaure M, Thiounn N, Scotte F et al. (2002) Collecting duct carcinomas of the kidney: a clinicopathological study of 9 cases. J Urol 170:1138–1140
Pickhardt PJ (1999) Collecting duct carcinoma arising in a solitary kidney: imaging findings. Clin Imaging 23:115–118
Pickhardt PJ, Siegel CL, McLarney JK (2001) Collecting duct carcinoma of the kidney: Are imaging findings suggestive of the diagnosis? Am J Roentgenol 176:627–633
Rumpelt HJ, Störkel S, Moll R et al. (1991) Bellini duct carcinoma: further evidence for this rare variant of renal cell carcinoma. Histopathology 18:115–122
Singh I, Nabi G (2002) Bellini duct carcinoma: review of diagnosis and management. Int Urol Nephrol 34:91–95
Sironi M, Delpiano C, Claren R et al. (2003) New cytological findings on fine-needle aspiration on renal collecting duct carcinoma. Diagn Cytopathol 29:239–240
Srigley JR, Eble JN (1998) Collecting duct carcinoma of kidney. Semin Diagn Pathol 15:54–67
Thoenes W, Störkel S, Rumpelt HJ (1986) Histopathology and classification of renal cell tumors (adenomas, oncocytomas and carcinomas). The basic cytological and histopathological elements and their use for diagnostics. Pathol Res Pract 181:125–143
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Kuk Yoon, S., Hee Rha, S. (2006). Collecting Duct Carcinoma. In: Guermazi, A. (eds) Imaging of Kidney Cancer. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-30003-1_11
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