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The Critically Ill Cardiac Surgery Patient: How to Avoid Postoperative Catastrophe?

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Yearbook of Intensive Care and Emergency Medicine 2005

Part of the book series: EN]Yearbook of Intensive Care and Emergency Medicine ((volume 2005))

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References

  1. Veering BT (1999) Management of anaesthesia in the elderly patients. Curr Opin Anaesthesiol 12:333–336

    Article  Google Scholar 

  2. Harris J (1999) Cardiac surgery in the elderly. Heart 82:119–120

    PubMed  Google Scholar 

  3. Christenson JT, Simonet F, Schmuziger M (1999) The influence of age on the outcome of primary coronary artery bypass grafting. J Cardiovasc Surg 40:333–338

    Google Scholar 

  4. Wick G, Grubeck-Loebenstein B (1997) The aging immune system: primary and secondary alterations of immune reactivity in the elderly. Exp Gerontol 32:401–413

    Article  PubMed  Google Scholar 

  5. Priebe HJ (2000) The aged cardiovascular risk patient. Br J Anaesth 85:763–778

    Article  PubMed  Google Scholar 

  6. Amano HH, Yoshida S, Takahashi A, Nagano N, Kohmoto T (2000) Coronary artery bypass grafting in the elderly. Chest 117:1262–1270

    PubMed  Google Scholar 

  7. MacDonald P, Johnstone D, Rockwood K (2000) Coronary artery bypass surgery for elderly patients: is our practice based on evidence or faith? CMAJ 162:1005–1006

    PubMed  Google Scholar 

  8. Cook TM, Day CJ (1998) Hospital mortality after urgent and emergency laparatomy in patients aged 65 years and over. Risk and prediction of risk using multiple logistic regression analysis. Br J Anaesth 80:776–781

    PubMed  Google Scholar 

  9. Rady MY (1998) Perioperative determinants of morbidity and mortality in elderly patients undergoing cardiac surgery. Crit Care Med 26:225–235

    Article  PubMed  Google Scholar 

  10. Boyle EM, Pohlman TH, Johnson MC, Verrier ED (1997) Endothelial cell injury in cardiovascular surgery: the systemic inflammatory response. Ann Thorac Surg 63:277–284

    Article  PubMed  Google Scholar 

  11. Royston D (1997) The inflammatory response and extracorporeal circulation. J Cardiothorac Vasc Anesth 11:341–354

    Article  PubMed  Google Scholar 

  12. Miller BE, Levy JH (1997) The inflammatory response to cardiopulmonary bypass. J Cardiothorac Vasc Anesth 11:355–366

    PubMed  Google Scholar 

  13. Németh ZH, Haskó G, Szabó C, Vizi ES (1997) Amrinone and theophylline differentially regulate cytokine and nitric oxide production in endotoxemic mice. Shock 7:371–375

    PubMed  Google Scholar 

  14. Ichioka S, Nakatsuka T, Sato Y, Shibata M, Kamiya A, Harii K (1998) Amrinone, a selective phosphodiesterase III inhibitor, improves microcirculation and flap survival: a comparative study with prostaglandin E. J Surg Res 75:42–48

    Article  PubMed  Google Scholar 

  15. Boldt J, Brosch C, Suttner S, Piper SN, Lehmann A, Werling C (2002) Prophylactic use of the phospodiesterase III inhibitor enoximone in elderly cardiac surgery patients: effect on hemodynamics, inflammation, and markers of organ function. Intensive Care Med 28:1462–1469

    PubMed  Google Scholar 

  16. Hill GE (1998) Cardiopulmonary bypass-induced inflammation: is it important? J Cardiothorac Vasc Anesth 12(suppl):S21–S25

    Google Scholar 

  17. Verrier ED, Morgan EN (1998) Endothelial response to cardiopulmonary bypass surgery. Ann Thorac Surg 66:S17–S19

    Article  PubMed  Google Scholar 

  18. Paret G, Prince T, Keller N, et al (2000) Plasma soluble E-selectin after cardiopulmonary bypass in children: is it a marker of the post-operative care? J Cardiothorac Vasc Anesth 14:433–437

    Article  PubMed  Google Scholar 

  19. Toft P, Christiansen K, Tönnesen E, Noelsen CH, Lillevang S (1998) Changes in adhesion molecule expression and oxidative burst activity of granulocytes and monocytes during open-heart surgery with cardiopulmonary bypass compared with abdominal surgery. Eur J Anaesthesiol 31:283–288

    Google Scholar 

  20. Blease K, Burke Gaffney A, Hellewell PG (1998) Modulation of cell adhesion molecule expression and function on human lung microvascular endothelial cells by inhibition of phosphodiesterase 3 and 4. Br J Pharmacol 124:229–237

    Article  PubMed  Google Scholar 

  21. Orii R, Sugawara Y, Hayashida M, et al (2000) Effects of amrinone on ischaemia-reperfusion injury in cirrhotic patients undergoing hepatectomy: a comparative study with prostaglandin E1. Br J Anaesth 85:389–395

    PubMed  Google Scholar 

  22. Fiddian-Green RG (1990) Gut mucosal ischemia during cardiac surgery. Sem Thorac Cardiovasc Surg 2:389–399

    Google Scholar 

  23. Mythen MG, Webb AR (1994) The role of gut mucosal hypoperfusion in the pathogenesis of postoperative organ dysfunction. Intensive Care Med 20:203–209

    Article  PubMed  Google Scholar 

  24. McNicol L, Andersen LW, Liu G, Doolan L, Beak L (1999) Markers of splanchnic perfusion and intestinal translocation of endotoxins during cardiopulmonary bypass: Effects of dopamine and milrinone. J Cardiothorac Vasc Anesth 13:292–298

    Article  PubMed  Google Scholar 

  25. Roques F, Nashef SA, Michel P, et al (1999) Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients. Eur J Cardiothorac Surg 15:816–822

    Article  PubMed  Google Scholar 

  26. Lindeman RD (1992) Changes in renal function with aging: Implications for treatment. Drugs Aging 2:423–431

    PubMed  Google Scholar 

  27. Zurier RB, Weismann G, Hoffstein S, Kammermann S, Thai HH (1974) Mechanisms of lysosomal enzyme release from human leukocytes. Effects of cAMP and cGMP, autonomic agonists, and agents which affect microtubule function. J Clin Invest 53:297–309

    PubMed  Google Scholar 

  28. London MJ (2003) Perioperative beta blockade: Facts and controversies. Ann Cardiac Anaesth 6:117–125

    Google Scholar 

  29. Ferguson TB Jr, Coombs LP, Peterson ED; Society of Thoracic Surgeons National Adult Cardiac Surgery Database (2002) Preoperative beta-blocker use and mortality and morbidity following CABG surgery in North America. JAMA 287:2221–2277

    Article  PubMed  Google Scholar 

  30. Wei S, Chow LT, Sanderson JE (2000) Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction. J Am Coll Cardiol 36:276–281

    Article  PubMed  Google Scholar 

  31. Port JD, Bristow MR (2001) Altered beta-adrenergic receptor gene regulation and signaling in chronic heart failure. J Mol Cell Cardiol 33:887–905

    Article  PubMed  Google Scholar 

  32. Amory DW, Grigore A, Amory JK, et al (2002) Neuroprotection is associated with beta-adrenergic receptor antagonists during cardiac surgery: evidence from 2575 patients. J Cardiothorac Vasc Anesth 16:270–277

    Article  PubMed  Google Scholar 

  33. Boldt J, Kling D, Zickmann B, Dapper F, Hempelmann G (1990) Haemodynamic effects of the phosphodiesterase inhibitor enoximone in comparison with dobutamine in esmololtreated cardiac surgery patients. Br J Anaesth 64:611–616

    PubMed  Google Scholar 

  34. Metra M, Nodari S, D'Aloia A, et al (2002) Beta-blocker therapy influences the hemodynamic response to inotropic agents in patients with heart failure: a randomized comparison of dobutamine and enoximone before and after chronic treatment with metoprolol or carvedilol. J Am Coll Cardiol 40:1248–1258

    Article  PubMed  Google Scholar 

  35. Boldt J, Brosch Ch, Lehmann A, Suttner St, Isgro F (2004) The prophylactic use of the beta-blocker esmolol in combination with phosphodiesterase inhibitor III enoximone in the elderly cardiac surgery patient. Anesth Analg 99:1009–1117

    Article  PubMed  Google Scholar 

  36. Galley HF (1999) Cytokine-endothelial cell interaction. Br J Intensive Care 9:147–151

    Google Scholar 

  37. Seekamp A, Jochum M, Ziegler M, et al (1998) Cytokines and adhesion molecules in elective and accidental trauma-related ischemia/reperfusion. J Trauma 44:874–882

    PubMed  Google Scholar 

  38. Hochman JS (2003) Cardiogenic shock complicating acute myocardial infarction: expanding the paradigm. Circulation 107:2998–3002

    PubMed  Google Scholar 

  39. Sorsa T, Heikkinen S, Abott MB, et al (2001) Binding of levosimendan, a calcium sensitizer, to cardiac troponin C. J Biol Chem 276:9337–9343

    Article  PubMed  Google Scholar 

  40. Ukkonen H, Saraste M, Akkila J, et al (2000) Myocardial efficiency during levosimendan infusion in congestive heart failure. Clin Pharmacol Ther 68:522–531

    Article  PubMed  Google Scholar 

  41. Remme WJ (1993) Inodilator therapy for heart failure. Early, late, or not at all? Circulation 87(5 suppl):IV97–IV107

    PubMed  Google Scholar 

  42. Yokoshiki H, Katsube Y, Sunagawa M, Sperelakis N (1997) Levosimendan, a novel CA2+ sensitizer, activates the ATP-sensitive K+ channel in rat ventricular cells. J Pharmacol Exp Ther 283:375–383

    PubMed  Google Scholar 

  43. Webb JG, Lowe AM, Sanborn TA, et al (2003) Percutaneous coronary intervention for cardiogenic shock in the SHOCK trial. The SHOCK investigators. J Am Coll Cardiol 42:1380–1386

    Article  PubMed  Google Scholar 

  44. Jamali IN, Kersten JR, Pagel PS, Hettrick DA, Warltier DC (1997) Intracoronary levosimendan enhances contractile function of stunned myocardium. Anesth Analg 85:23–29

    Article  PubMed  Google Scholar 

  45. Perrault LP, Menasche P (1999) Preconditioning: can nature's shield be raised against surgical ischemic-reperfusion injury? Ann Thorac Surg 68:1988–1994

    Article  PubMed  Google Scholar 

  46. Haikala H, Kaheinen P, Levijoki J, Linden IB (1997) The role of cAMP-and cGMP-dependent protein kinases in the cardiac actions of the new calcium sensitizer, levosimendan. Cardiovasc Res 34:536–546

    Article  PubMed  Google Scholar 

  47. Moiseyev VS, Poder P, Andrejevs N, et al (2002) Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventricular failure due to an acute myocardial infarction. A randomized, placebo-controlled, double-blind study (RUSSLAN). Eur Heart J 23:1422–1432

    Article  PubMed  Google Scholar 

  48. Hunt SA, Baker DW, Chin MH, et al (2001) ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: Executive summary a report of the American College of Cardiology/American Heart Association task force on practice guidelines (committee to revise the 1995 guidelines for the evaluation and management of heart failure). Circulation 104:2996–3007

    PubMed  Google Scholar 

  49. Delle Karth G, Buberl A, Geppert A, et al (2003) Hemodynamic effects of a continuous infusion of levosimendan in critically ill patients with cardiogenic shock requiring catecholamines. Acta Anaesthesiol Scand 47:1251–1256

    Article  PubMed  Google Scholar 

  50. Lehmann A, Lang J, Boldt J, Isgro F, Kiessling AH (2004) Levosimendan in patients with cardiogenic shock undergoing surgical revascularization: a case series. In electronic publication: Med Sci Monit 10:MT89–MT93

    Google Scholar 

  51. Lehmann A, Boldt J, Lang J, Isgro F, Blome M (2003) Is levosimendan an inoprotective drug in patients with acute coronary syndrome undergoing surgical revascularization? Anasthesiol Intensivmed Notfallmed Schmerzther 38:577–582

    Article  PubMed  Google Scholar 

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Authors
  1. J. Boldt
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  2. A. Lehmann
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Editor information

Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Head) (Head)

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Boldt, J., Lehmann, A. (2005). The Critically Ill Cardiac Surgery Patient: How to Avoid Postoperative Catastrophe?. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 2005. EN]Yearbook of Intensive Care and Emergency Medicine, vol 2005. Springer, New York, NY. https://doi.org/10.1007/0-387-26272-5_14

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  • DOI: https://doi.org/10.1007/0-387-26272-5_14

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-3-540-23476-0

  • Online ISBN: 978-0-387-26272-7

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