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Structure and Physics of Viruses

An Integrated Guide

  • Book
  • Oct 2024
  • Latest edition

Overview

Editors:
  1. Mauricio G. Mateu

    1. Department of Molecular Biology of the Universidad Autonoma de Madrid, Centro de Biología Molecular "Severo Ochoa" (CSIC_UAM), Madrid, Spain

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  • The only integrated book on structural and physical virology
  • Fully updated account of the structure, dynamics and physics of viral particles
  • A perfect resource for postgraduates and researchers working on structural and/or physical virology

Part of the book series: Subcellular Biochemistry (SCBI, volume 105)

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About this book

The second edition of this book provides a completely updated account of the structure, dynamics, and physics of viral particles: from the moment they emerge by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognize and infect a new host cell and cease to exist as they lose their physical integrity to initiate a new infectious cycle.

New insights into the structure of viruses, their physical properties, and mechanisms of action, derived from results obtained in the last decade, have been included, as well as other (bio)physical techniques to study the structure or dynamics of virus particles and components. These include new advances in high-resolution electron cryomicroscopy; novel approaches in the use of electron cryotomography or the application of soft X-ray tomography to study viruses in the infected cell; high-speed atomic force microscopy to study virus assembly and dynamics. The development of antiviral drugs and vaccines with virus-like particles.

New chapters on the technological applications of modified viral particles or the physical study of the virus-liquid interface have been included in this second edition, which is still aimed primarily at Master's students, Ph.D. students, and postdoctoral researchers with degrees in biology, chemistry, physics or related scientific disciplines who have an interest in or are working with viruses, providing an up-to-date overview of many important concepts, techniques, studies and applications in structural and physical virology for specialized researchers working with viruses, regardless of their field of specialization, covering the latest research together with fundamental concepts and well-established facts.

In short, this book is basic enough to be used by undergraduate and Ph.D. students, but advanced and up-to-date enough for experienced scientists with an interest in structural and/or physical virology.

Keywords

  • Virus Architecture
  • Virus Function
  • Virus Properties
  • Viral Infection
  • Virus Structure
  • Nucleic Acid Packaging
  • Physical Virology

Editors and Affiliations

  • Department of Molecular Biology of the Universidad Autonoma de Madrid, Centro de Biología Molecular "Severo Ochoa" (CSIC_UAM), Madrid, Spain

    Mauricio G. Mateu

About the editor

Mauricio G. Mateu is a Full Professor of Biochemistry and Molecular Biology at the Universidad Autonoma de Madrid (UAM), and a Group Leader at the Centro de Biología Molecular "Severo Ochoa" (Spanish Research Council-UAM). He combined training in biochemistry, molecular virology, and protein engineering in three prestigious laboratories, respectively led by Profs. Severo Ochoa and Esteban Domingo in Madrid, Spain, and Alan R. Fersht in Cambridge, UK, to establish a research line on the structural basis of virus function. His group uses protein engineering and biological, biochemical, and biophysical approaches, including atomic force microscopy, to understand the relationships between atomic structure, conformational stability and dynamics, physical properties, and biological function of viruses. His studies on viruses during the last 35 years have involved multidisciplinary and interdisciplinary collaborations with theoretical and condensed matter physicists, organic chemists, biochemists, structural biologists, biophysicists, and molecular virologists. He is the author of over 150 scientific publications, including over 110 original research articles.

Bibliographic Information

  • Book Title: Structure and Physics of Viruses

  • Book Subtitle: An Integrated Guide

  • Editors: Mauricio G. Mateu

  • Series Title: Subcellular Biochemistry

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2024

  • Hardcover ISBN: 978-3-031-65186-1Due: 30 October 2024

  • Softcover ISBN: 978-3-031-65189-2Due: 30 October 2025

  • eBook ISBN: 978-3-031-65187-8Due: 30 October 2024

  • Series ISSN: 0306-0225

  • Series E-ISSN: 2542-8810

  • Edition Number: 2

  • Number of Pages: XVII, 884

  • Number of Illustrations: 28 b/w illustrations, 179 illustrations in colour

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