Overview
- Editors:
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Andrew Robinson
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Centre for Applied Microbiology and Research, Porton Down, UK
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Graham H. Farrar
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Centre for Applied Microbiology and Research, Porton Down, UK
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Christopher N. Wiblin
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Centre for Applied Microbiology and Research, Porton Down, UK
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About this book
The production of a book devoted to Vaccine Protocols has proved to be a complex task; the variety of procedures required to design, develop, pro duce, and assess a vaccine is immense and covers aspects of chemistry, bio chemistry, molecular biology, and immunology. Many of the previous volumes in the Methods in Molecular Biology series provide the background required for work on vaccines; of particular interest are the volumes on Immunochemi cal Protocols, Practical Molecular Virology, Proteins, and Nucleic Acids. In the volume on Vaccine Protocols, we have tried to cover the latest scientific methods for the design, production, and assessment of vaccines against viruses, bacteria, and parasites. Essentially, the volume is comprised of three basic chapter types. First, a number of chapters describe in detail the development and production of vac cines by specific techniques, including genetic manipulation of viruses or bac teria to produce live attenuated vaccines or inactivated toxins, and the production of synthetic peptides and conjugate vaccines. Second, a similar number of chapters describe more general techniques that can be used for the formulation, delivery, and assessment of immune responses to vaccines.
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Table of contents (22 protocols)
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- Alan Warnes, Anthony R. Fooks
Pages 33-45
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- Richard J. Anderson, L. Patricia Londoño, Derek J. Pickard, Gordon Dougan
Pages 47-62
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- Riny Janssen, Jan Tommassen
Pages 63-74
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- Mariagrazia Pizza, Maria Rita Fontana, Vincenzo Scarlato, Rino Rappuoli
Pages 91-109
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- Carla C. A. M. Peeters, Patrick R. Lagerman, Odo de Weers, Lukas A. Oomen, Peter Hoogerhout, Michel Beurret et al.
Pages 111-133
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- Duncan E. S. Stewart-Tull
Pages 135-139
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- Duncan E. S. Stewart-Tull
Pages 141-145
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- Duncan E. S. Stewart-Tull
Pages 147-151
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- Duncan E. S. Stewart-Tull
Pages 153-155
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- David J. M. Lewis, Christopher M. M. Hayward
Pages 187-195
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- Paddy Farrington, Elizabeth Miller
Pages 251-268
Reviews
"...a valuable basic reference manual of vaccine related laboratory procedures...strongest in the area of vaccine development and delivery technology...especially valuable to those new to the field of vaccine development and formulation." -Doody's Health Sciences Book Review Journal
" ...this book should prove to be a valuable aid to all those seeking to produce improved or novel vaccines." -Unlisted Drugs
"...serves as a valuable source of information on nonviral and viral gene delivery..." - Pharmaceutical Research
"...useful and will serve many in the vaccine reseach and development community quite well...provides practical advice, a commodity that is ofen difficult to find in printed and scientific and manufacturing literature." - Clinical Infectious Diseases