Overview
- Vast information on PEG and PEG-conjugates collected in one book
- Competent authorship from academia and industry assures comprehensive information
- Includes supplementary material: sn.pub/extras
Part of the book series: Milestones in Drug Therapy (MDT)
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About this book
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.
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Keywords
Table of contents (16 chapters)
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Front Matter
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Back Matter
Reviews
From the reviews:
“The volume is dedicated to the recent advances on PEGylation and PEGylated compunds. It represents an excellent update in the evolution of this field, from nanoscience to clinical applications. The book provides an excellent update in this rapidly evolving field. … This valuable volume which will spark the interest of both researchers and clinicians contributes to a better understanding of polymer therapeutics.” (Magdalena Moisei, Romanian Journal of Biochemistry, Vol. 47 (2), 2010)Editors and Affiliations
Bibliographic Information
Book Title: PEGylated Protein Drugs: Basic Science and Clinical Applications
Editors: Francesco M. Veronese
Series Title: Milestones in Drug Therapy
DOI: https://doi.org/10.1007/978-3-7643-8679-5
Publisher: Birkhäuser Basel
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Birkhäuser Basel 2009
Hardcover ISBN: 978-3-7643-8678-8Published: 18 September 2009
eBook ISBN: 978-3-7643-8679-5Published: 30 December 2009
Series ISSN: 2296-6056
Series E-ISSN: 2296-6064
Edition Number: 1
Number of Pages: IX, 290
Topics: Pharmacology/Toxicology, Immunology, Biotechnology, Medical Biochemistry, Medicinal Chemistry