Overview
- A comprehensive overview of obesity and lipotoxicity
- Discusses the mechanisms of obesity and possibilities for the development of new treatment strategies
- Overview of the biochemical pathways leading to obesity-related metabolic disorders
- Includes supplementary material: sn.pub/extras
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 960)
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About this book
Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.
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Keywords
Table of contents (26 chapters)
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Front Matter
Reviews
“The aim is to discuss the many critical and complex topics that trigger obesity with the hope that the book will encourage and further the research of scientists and practitioners who are interested in obesity. … This book is intended as a useful resource for clinicians and basic science researchers such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, and cardiologists, as well as students who are interested in this field.” (L. Anne Gilmore, Doody's Book Reviews, September, 2017)
Editors and Affiliations
Bibliographic Information
Book Title: Obesity and Lipotoxicity
Editors: Ayse Basak Engin, Atilla Engin
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-319-48382-5
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017
Softcover ISBN: 978-3-319-83928-8Published: 12 June 2018
eBook ISBN: 978-3-319-48382-5Published: 05 June 2017
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VIII, 624
Number of Illustrations: 12 b/w illustrations, 35 illustrations in colour
Topics: Biochemistry, general, Pharmacology/Toxicology, Endocrinology