Overview
- Examines the involvement of non-neuronal cells in chronic pain
- Presents potential new treatments for chronic pain such as specialized immune cell therapy
- Offers an introduction to acute and chronic pain in the context of the opioid crisis and the COVID pandemic
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About this book
As lifespans increase, more people around the world find themselves victims of chronic pain. In spite of this, treatment options continue to be severely limited. Anti-inflammatory drugs can only do so much, while painkillers like opioids have led to crippling addictions and fatal overdoses. The subject of the book is the role of immune cells, including glial cells, and neuroimmune interactions in chronic pain. The book begins by examining the preclinical and clinical evidence supporting the involvement of non-neuronal cells in chronic pain. It discusses the interactions between non-neuronal cells and neurons in the regulation of chronic pain. It then presents the implications of these findings, including promising and emerging treatments such as specialized pro-resolving mediators (SPMs, such as resolvins and protectins), immune cell therapy, and complementary and alternative medicine, as well as neuromodulation and regenerative medicine, which may prove to be theturning point for hundreds of millions of patients world-wide who struggle to escape from the shadow of chronic pain. The book presents ground-breaking research that will alter current perspectives on chronic pain.
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Keywords
Table of contents (16 chapters)
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Front Matter
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Back Matter
Editors and Affiliations
About the editors
Dr. Ru-Rong Ji, is a Professor of Anesthesiology, and the Director of the Center for Translational Pain Medicine at the Duke University Medical Center in Durham, North Carolina, USA.
Dr. Jianguo Cheng is Professor of Anesthesiology and the Director of Cleveland Clinic Multidisciplinary Pain Medicine Fellowship Program. He works in the departments of Pain Management and Neurosciences at the Cleveland Clinic in Cleveland, Ohio, USA. He is Past President of the American Academy of Pain Medicine.
Jasmine Ji is a Neuroscience student at Wellesley College in Wellesley, Massachusetts, USA.
Bibliographic Information
Book Title: Neuroimmune Interactions in Pain
Book Subtitle: Mechanisms and Therapeutics
Editors: Ru-Rong Ji, Jianguo Cheng, Jasmine Ji
DOI: https://doi.org/10.1007/978-3-031-29231-6
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023
Hardcover ISBN: 978-3-031-29230-9Published: 06 May 2023
Softcover ISBN: 978-3-031-29233-0Published: 07 May 2024
eBook ISBN: 978-3-031-29231-6Published: 05 May 2023
Edition Number: 1
Number of Pages: X, 364
Number of Illustrations: 4 b/w illustrations, 41 illustrations in colour
Topics: Neurosciences, Pain Medicine, Neurology, Anesthesiology