Overview
- Provides an up-to-date review of the basic science of botulinum toxins and their therapeutic applications
- Discusses the clinical approach to using botulinum toxin therapy, and thoroughly reviews the major therapeutic applications of botulinum toxins
- Reviews both the science and therapy of currently approved botulinum toxins and the development of novel botulinum toxins
Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 263)
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About this book
In a rapidly progressing field, Botulinum Toxin Therapy provides both clinicians and basic researchers with the latest science on the structure and function of botulinum toxins and the use of these toxins to treat a wide variety of diseases. Part 1 of the book reviews the basic science of botulinum toxins including advances in our understanding of the molecular structure and mechanism of action of botulinum toxins. This section also discusses the manufacturing and formulation of botulinum toxins for clinical use and the development of novel therapeutic toxins for the future. Part 2 reviews the use of botulinum toxins in clinical practice. It discusses the clinical pharmacology of botulinum toxin drugs and their use in a wide variety of clinical conditions including headache, spasticity, pain, disorders of the genitourinary and gastrointestinal tract, strabismus, and medical aesthetics.
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Keywords
- Botulinum toxin, toxin
- Endopeptidase
- Synaptosomal associated protein (SNAP)
- SNAP 25
- SNARE (SNAP Receptor)
- Epidermal growth factor
- abobotulinumtoxinA
- incobotulinumtoxinA
- onabotulinumtoxinA
- rimabotulinumtoxinB
- Strabismus
- Blepharospasm
- Migraine
- Glabellar lines
- Dystonia
- Cerebral palsy
- Hyperhidrosis
- Overactive bladder
- psychopharmacology
Table of contents (21 chapters)
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Front Matter
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Basic Sciences
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Front Matter
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Clinical Practice
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Front Matter
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Editors and Affiliations
Bibliographic Information
Book Title: Botulinum Toxin Therapy
Editors: Scott M. Whitcup, Mark Hallett
Series Title: Handbook of Experimental Pharmacology
DOI: https://doi.org/10.1007/978-3-030-66306-3
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2021
Hardcover ISBN: 978-3-030-66305-6Published: 06 January 2021
Softcover ISBN: 978-3-030-66308-7Published: 07 January 2022
eBook ISBN: 978-3-030-66306-3Published: 05 January 2021
Series ISSN: 0171-2004
Series E-ISSN: 1865-0325
Edition Number: 1
Number of Pages: VIII, 289
Topics: Pharmacology/Toxicology, Psychopharmacology, Neurosciences