Overview
- A compendium of the most recent and advanced methods applied to the rapidly expanding field of telomerase inhibition
- Provides the researcher with a diverse and comprehensive set of tools
Part of the book series: Methods in Molecular Biology (MIMB, volume 405)
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About this book
Due in part to the selective nature of telomerase inhibition as an anticancer approach, the field has expanded considerably in the past decade. The recent advances in methods of telomerase inhibition encompass many different areas of research including molecular biology, cell biology, biochemistry, oncology and gerontology. Telomerase Inhibition provides methods and protocols for those researchers. The techniques described in this book should provide the researcher with a diverse and comprehensive set of tools with which to study telomerase inhibition. Leaders in the field provide recently developed methods that have widespread application such as targeting the telomerase holoenzyme, its RNA template and other elements associated with telomerase activity. Additional methods involving the screening of telomerase inhibitors and telomerase inhibition combined with other chemotherapeutic agents are presented. This text, on the cutting edge of the field, will provide investigators with the most recent methods applied to the expanding field of telomerase inhibition.
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Keywords
Table of contents (14 protocols)
Reviews
From the reviews:
"This book contains 14 chapters by active players in the telomerase field. … Overall this book will be a useful resource for researchers performing telomerase-related experiments." (Lionel Guittat and Jean-Louis Mergny, ChemMedChem, Issue 3, 2008)
Editors and Affiliations
Bibliographic Information
Book Title: Telomerase Inhibition
Book Subtitle: Strategies and Protocols
Editors: Lucy G. Andrews, Trygve O. Tollefsbol
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-60327-070-0
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2007
Hardcover ISBN: 978-1-58829-683-2Published: 29 November 2007
Softcover ISBN: 978-1-61737-716-7Published: 12 December 2011
eBook ISBN: 978-1-60327-070-0Published: 03 February 2008
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: X, 193
Topics: Cell Biology, Cancer Research, Human Genetics, Biochemistry, general