Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1325)
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About this book
This volume focuses on malaria vaccinology, and introduces researchers to a complete overview of the protocols and tools used by molecular and cellular malariologists. The chapters within this book talk about interventions concerning all aspects of life cycle progression--measuring antibody responses to blood stage parasite survival, the T Cell responses engendered by attenuated sporozoite vaccinations, and the unique effect on transmission of antibodies that target the mosquito stage of the life cycle. Additionally, methods concerning the ability to generate targeted gene deletions and replacements in the genome of Plasmodium parasites convey how Plasmodium parasite phenotypes can be created to precise specifications. More recently, the potential power of humanized mouse models of disease progression have been demonstrated and are also discussed in the book. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Malaria Vaccines: Methods and Protocols is a useful and unique resource for any aspiring malaria vaccinologists because of the volume's exquisitely detailed methodologies that are not typically found in published literature.
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Keywords
Table of contents (22 protocols)
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Pre-erythrocytic Stages
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Erythrocytic Stages
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Malaria Vaccines
Book Subtitle: Methods and Protocols
Editors: Ashley Vaughan
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-2815-6
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2015
Hardcover ISBN: 978-1-4939-2814-9Published: 10 October 2015
Softcover ISBN: 978-1-4939-4902-1Published: 23 August 2016
eBook ISBN: 978-1-4939-2815-6Published: 08 October 2015
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 305
Number of Illustrations: 7 b/w illustrations, 30 illustrations in colour
Topics: Immunology, Vaccine