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About this book
PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status.
Not surprising, given these roles, there is intense investigation of the roles of bHLH-PAS proteins in issues of human health including: (1) cancer induction, (2) cancer growth and vascularity, (3) birth defects, including Down syndrome, (4) appetite control and obesity, (5) sleep rhythm disorders, and (6) mental health disorders such as social interactions and learning.
PAS proteins encompass many fields of biology, and scientists who work in these fields (circadian rhythms, oxygen regulation, toxin metabolism, bacterial sensors, and development) are an audience, particularly those who actively work on PAS proteins and researchers interested in transcriptional control, signal transduction, and evolution.
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Table of contents (10 chapters)
Editors and Affiliations
Bibliographic Information
Book Title: PAS Proteins: Regulators and Sensors of Development and Physiology
Editors: Stephen T. Crews
DOI: https://doi.org/10.1007/978-1-4615-0515-0
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Kluwer Academic Publishers 2003
Hardcover ISBN: 978-1-4020-7586-5Published: 30 September 2003
Softcover ISBN: 978-1-4613-5115-3Published: 21 October 2012
eBook ISBN: 978-1-4615-0515-0Published: 06 December 2012
Edition Number: 1
Number of Pages: XIII, 263
Topics: Protein Science, Biochemistry, general, Human Genetics, Medical Microbiology, Neurosciences, Oncology