Overview
- Provides a comprehensive picture of the unique global role Gadd45 genes play as stress sensors and the molecular pathways involved
- The functions of Gadd45 proteins are mediated by protein-protein interactions that modulate structure/function of other cellular proteins implicated in cell cycle regulation
- Gadd45 proteins are implicated in cell cycle arrest, DNA demethylation & repair, apoptosis, cell survival, genomic stability, inflammation, & in response to physiological and oncogenic stress
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 793)
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Table of contents (7 chapters)
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Bibliographic Information
Book Title: Gadd45 Stress Sensor Genes
Editors: Dan A. Liebermann, Barbara Hoffman
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-1-4614-8289-5
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2013
Softcover ISBN: 978-1-4939-5390-5Published: 23 August 2016
eBook ISBN: 978-1-4614-8289-5Published: 08 October 2013
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: X, 134
Number of Illustrations: 7 b/w illustrations, 11 illustrations in colour
Topics: Gene Function, Biochemistry, general, Human Genetics