Abstract
Thirty-five rats were injected with varying doses of scopolamine, methyl scopolamine, and saline before extinction of a continuously reinforced response. Methyl scopolamine and low doses of scopolamine speeded extinction, whereas higher doses of scopolamine led to responding similar to that of saline controls. It is suggested that the relatively weak tendency to respond after CRF training and the drastic switch to extinction from CRF maximized the disruptive peripheral effects of scopolamine, and as a result higher doses were required to show prolongation of extinction.
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This research was supported by a grant from the Chancellor’s Fund of Lakehead University and by National Research Council of Canada Grant APA 268.
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McKim, W.A. The effects of scopolamine on the extinction of a continuously reinforced response. Psychon Sci 20, 281–282 (1970). https://doi.org/10.3758/BF03329067
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DOI: https://doi.org/10.3758/BF03329067