Abstract
The influenza virus enzyme neuraminidase is an attractive antiviral target because its active site is highly conserved among many influenza A and B strains. Neuraminidase inhibitors are an exciting new class of antiviral drug that should help in the prevention and treatment of influenza infection. Encouraging new clinical data on the 2 most advanced neuraminidase inhibitors, GS-4104 and zanamivir, were presented at the 38th Interscience Conference on Antimicrobial Agents and Chemotherapy [ San Diego, US; September 1998 ]. These data suggest that both agents could be useful in the prophylaxis and treatment of influenza A and B.
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Prentice, K. Neuraminidase inhibitors offer relief from the flu. Inpharma Wkly. 1160, 7–8 (1998). https://doi.org/10.2165/00128413-199811600-00016
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DOI: https://doi.org/10.2165/00128413-199811600-00016