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Despite the discovery of leukotrienes and other putative allergic mediators, histamine remains the only compound with a confirmed role in allergy, said Dr David Roberts from Laboratorios Almirall, Spain. ‘That’s why we feel there is room for another antihistamine’ , he added. At the 16th European Congress of Allergology and Clinical Immunology [ Madrid, Spain; June 1995 ], Rhône-Poulenc Rorer, Fisons and Almirall held a joint satellite symposium to review the second-generation antihistamine ebastine. It was concluded that ebastine is a well-tolerated nonsedating antihistamine, which appears to be free of serious adverse cardiovascular events. Thus, it can be considered as a useful alternative to other first-line treatment options.
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Wiseman, L. Ebastine provides new option for treating allergies. Inpharma Wkly. 999, 13–14 (1995). https://doi.org/10.2165/00128413-199509990-00026
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DOI: https://doi.org/10.2165/00128413-199509990-00026