Abstract
A series of 6-imino-1-aryl-4-(arylimino)-1,3,5-triazinane-2-thione derivatives are synthesized by cyclization of 1-aryl-3-cyanoguanidine with aryl isothiocyante in the presence of sodium methoxide under MW irradiation. Structures of the synthesized compounds 3a-j are elucidated from 1H and 13C NMR, MS, and IR, data. The synthesized compounds are evaluated for their antimicrobial activity against B. subtilis, S. aureus, P. aeruginosa, and E. Coli. Some compounds demonstrate promising activity against the tested strains.
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Ashok, D., Ganesh, A., Ravi, S., Vijaya Lakshmi, B., and Ramesh, B., Russ. J. Gen. Chem., 2014, vol. 4, no. 11, p. 2248. doi https://doi.org/10.1134/S1070363214110346
Zhao H., Liu, Y., Cui, Zh., Beattie, D., Gu, Y., and Wang, Q., J. Agric. Food Chem. 2011, vol. 59, p. 11711. doi https://doi.org/10.1021/jf203383s
Ravindra, S., Shinde., and Shridhar, D.S., Asian J. Chem., 2015, vol. 27, p. 4130. doi https://doi.org/10.14233/ajchem.2015.19114
Brzozowski, Z., Sączewski, F., and Gdaniec, M., Eur. J. Med. Chem. 2000, vol. 35, p. 1053. doi https://doi.org/10.1016/S0223-5234(00)01194-6
Sączewski, F., Bulakowska, A., Bednarski, P., and Grunert, R., Eur.J. Med. Chem. 2006, vol. 41, p. 219. doi https://doi.org/10.1016/j.ejmech.2005.10.013
Joseph, K.M., Patent EP0834507A1.
Kurzer, F. and Pitchfork, E.D., J. Chem. Soc., C, 1964, p. 3459. doi https://doi.org/10.1039/JR9640003459
Kaiser, D.W., Welcher, R.P., and Wystrach, V.P., US Patent 2820033, 1957
Kaiser, D.W., Welcher, R.P., and Wystrach, V.P., J. Am. Chem. Soc., 1959, vol. 81, p. 5655. doi https://doi.org/10.1021/ja01530a033
Rao, K., Indian J. Chem., 1969, vol. 7, p. 20.
Larhed, M., Moberg, C., and Hallberg, A., Acc. Chem. Res, 2002, vol. 35, p. 717. doi https://doi.org/10.1021/ar010074v
Lidstrom, P., Tierney, J., Wathey, B., and Westman, J., Tetrahedron., 2001, vol. 57, p. 9225. doi https://doi.org/10.1016/S0040-4020(01)00906-1
Elander, N., Jones, J.R., Lu, S.Y., and Stone-Elander, S., Chem. Soc. Rev., 2000, vol. 29, p. 239. doi https://doi.org/10.1039/A901713E
Linday, M.E., Practical Introduction to Microbiology, London: E & F. N. Spon Ltd., 1962.
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Siva Sankara Babu, T., Srinivasu, N., Saha, B. et al. Synthesis and Antimicrobial Activity of 1-Aryl-4-(arylimino)-6-iminohexahydro-1,3,5-triazine-2-thione Derivatives. Russ J Gen Chem 89, 824–830 (2019). https://doi.org/10.1134/S1070363219040303
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DOI: https://doi.org/10.1134/S1070363219040303