Abstract
A voltammetric procedure is developed for determining captopril in pharmaceuticals. It is based on the preliminary electrochemical accumulation of the captopril oxidation product on a platinum electrode in a 0.1 M HNO3 solution at 1.2 V versus a saturated silver-silver chloride electrode. The reduction current of the oxidation product is a linear function of captopril concentration in the range from 1.2 × 10−6 to 3.2 × 10−4 M. The determination limit is 9.2 × 10−7 M. The relative standard deviation is between 1 and 4%.
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Original Russian Text © G.K. Ziyatdinova, G.K. Budnikov, V.I. Pogorel’tsev, 2006, published in Zhurnal Analiticheskoi Khimii, 2006, Vol. 61, No. 8, pp. 865–867.
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Ziyatdinova, G.K., Budnikov, G.K. & Pogorel’tsev, V.I. Determination of captopril in pharmaceutical forms by stripping voltammetry. J Anal Chem 61, 798–800 (2006). https://doi.org/10.1134/S1061934806080144
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DOI: https://doi.org/10.1134/S1061934806080144