Abstract
To eliminate methanol inhibition of the activity of a lipase, methanotrophic bacteria, which can convert methanol into water and CO2, were introduced to the reaction of enantioselective hydrolysis of Naproxen methyl ester catalysed by lipase from Candida rugosa. Both the activity and stability of lipase were improved by the removal of methanol by the bacteria.
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Xu, Y., Chen, J., Xin, J. et al. Efficient microbial elimination of methanol inhibition for Naproxen resolution by a lipase. Biotechnology Letters 23, 1975–1979 (2001). https://doi.org/10.1023/A:1013738400504
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DOI: https://doi.org/10.1023/A:1013738400504