Abstract
Nucleic acid nanostructures with structural programmability, spatial addressability and excellent biocompatibility have drawn much attention in various biomedical applications, such as bioimaging, biosensing and drug delivery. In this review, we summarize the recent research progress in the field of bioimaging based on nucleic acid nanostructures with different imaging models, including fluorescent imaging(FI), magnetic resonance imaging(MRI), photoacoustic imaging(PAI) and positron emission tomography/computed tomography(PET/CT) imaging. We also discuss the remaining challenges and further opportunities involved in the bioimaging research based on nucleic acid nanostructures.
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Acknowledgements
This work was supported by the National Natural Science Foundation of China(Nos.22025201, 22077023 and 21721002), the National Basic Research Program of China(Nos.2016YFA0201601 and 2018YFA0208900), the Fund of the Beijing Municipal Science & Technology Commission, China (No.Z191100004819008), the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000), the Key Research Program of Frontier Sciences of CAS(No.QYZDB-SSW-SLH029), and the CAS Interdisciplinary Innovation Team, Youth Innovation Promotion Association CAS and K. C. Wong Education Foundation(No.GJTD-2018-03).
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Han, L., Wang, Y., Tang, W. et al. Bioimaging Based on Nucleic Acid Nanostructures. Chem. Res. Chin. Univ. 37, 823–828 (2021). https://doi.org/10.1007/s40242-021-1055-0
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DOI: https://doi.org/10.1007/s40242-021-1055-0