Abstract
Features of the metabolic syndrome, such as dyslipidaemia and inflammation, are risk factors contributing to insulin resistance and type 2 diabetes. However, little is known regarding the contribution of these features in the development of insulin resistance in the absence of obesity. We hypothesized that insulin resistance can develop without body weight gain because of dyslipidaemia and inflammation.
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Department of Pathology and Medical Biology, Molecular Genetics, University Medical Center Groningen, Groningen, The Netherlands. E-mail: N.Gruben@umcg.nl
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Gruben, N., Funke, A., Sheedfar, F. et al. PS2 - 12. Cholesterol induced inflammation does not exacerbate insulin resistance in lean Ldlr -/- mice. NED. TIJDSCHR. DIABET. 9, 98 (2011). https://doi.org/10.1007/s12467-011-0037-0
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DOI: https://doi.org/10.1007/s12467-011-0037-0