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PS1 - 3. The relationship between plasma and brain glucose levels under hypoglycemic conditions in humans

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Nederlands Tijdschrift voor Diabetologie Aims and scope

Abstract

Since glucose is the main source of energy for the brain, understanding the kinetics of brain glucose uptake under hypoglycemic conditions is highly important. Under normo- and hyperglycemic conditions the relationship between plasma and brain glucose levels is linear and behaves according to reversible Michaelis-Menten (MM) kinetics. In the present study brain glucose levels during hypoglycemia were measured by 13C magnetic resonance spectroscopy (MRS).

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Authors and Affiliations

  1. http://www.bsl.nl

    Kim C.C. van de Ven, Marinette van der Graaf & Arend Heerschap

  2. General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

    Cees J.J. Tack & Bastiaan E. de Galan

Authors
  1. Kim C.C. van de Ven
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  2. Marinette van der Graaf
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  3. Cees J.J. Tack
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  4. Arend Heerschap
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  5. Bastiaan E. de Galan
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Corresponding author

Correspondence to Kim C.C. van de Ven.

Additional information

Department of 1Radiology, 2Clinical Physics Laboratory, 3General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. E-mail: k.vandeven@rad.umcn.nl

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van de Ven, K., van der Graaf, M., Tack, C. et al. PS1 - 3. The relationship between plasma and brain glucose levels under hypoglycemic conditions in humans. NED. TIJDSCHR. DIABET. 9, 92 (2011). https://doi.org/10.1007/s12467-011-0028-1

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  • DOI: https://doi.org/10.1007/s12467-011-0028-1

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