Abstract
The Knoevenagel condensation of aromatic aldehydes with active methylene is an efficient reaction for carbon–carbon double bond formation. A rapid, efficient, and ecofriendly protocol for the Knoevenagel condensation of active methylene compounds with aldehydes has been developed with diethylamine functionalized polyethylene glycol-600 (PEG-600) as catalyst with good to excellent yields at room temperature without solvent.
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References
Bian Y J, Qing Y, Xiao L W and Li J T 2006 Chinese J. Org. Chem. 26 1165
Chalais S, Laszlo P and Mathy A 1985 Tetrahedron Lett. 26 4453
Villemin D and Martin B 1995 Synth. Commun. 25 2319
de la Cruz P, Diez-Barra E, Loupy A and Langa F 1996 Tetrahedron Lett. 37 1113
Mitra A K, De A and Karchaudhuri N 1999 Synth. Commun. 29 2731
Yadav J S, Reddy B V S, Basak A K, Visali B, Narsaiah A V and Nagaiah K 2004 Eur. J. Org. Chem. 546
Martin-Aranda R M, Ortega-Cantero E, Rojas-Cervantes M L, Vicente-Rodriguez M A and Banares-Munoz M A 2005 J. Chem. Technol. Biot. 80 234
Wang X T, Liang B and Wang J X 2007 Chem. Res. Appl. 5
Sun Q, Shi L X, Ge Z M, Cheng T M and Li R T 2005 Chinese. J. Chem. 23 745
Bennazha J, Zahouilly M, Boukhari A and Holt E M 2003 J. Mol. Catal. A: Chem. 202 247
Zahouily M, Bahlaouan B, Solhy A, Ouammou M and Sebti S 2003 React. Kinet. Catal. Lett. 78 129
Narsaiah A V, Basak A K, Visali B and Nagaiah K 2004 Synth. Commun. 34 2893
Deb M L and Bhuyan P J 2005 Tetrahedron Lett. 46 6453
List B, Doehring A, Fonseca M T H, Wobser K, van Thienen H, Torres R R and Galilea P L 2005 Adv. Synth. Catal. 347 1558
Tamami B and Fadavi A 2005 Catal. Commun. 6 747
Bass J D, Solovyov A, Pascall A J and Katz A 2006 J. Am. Chem. Soc. 128 3737
Liu Y, Liang J, Liu X, Fan J and Shang Z 2008 Chinese. Chem. Lett. 19 1043
Santamarta F, Verdía P and Tojo E 2008 Catal. Commun. 9 1779
Yue C, Mao A, Wei Y and Li M J 2008 Catal. Commun. 9 1571
Fang D, Fei Z H and Liu Z L 2008 Monatsh. Chem. 139 779
Ren Y M and Cai C 2007 Catal. Lett. 118 134
Parida K M, Rath D and Mol J 2009 Catal. A: Chem. 310 93
Liang X and Li S Z 1996 Ion Exchange and Adsorption 12 309
Wang X, Li L, Quan Z, Gong H, Ye H and Cao X 2009 Chinese. Chem. Lett. 20 651
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YE, W., JIANG, H. & YANG, XC. Diethylamine functionalized polyethylene glycol as a novel and efficient catalyst for Knoevenagel condensation. J Chem Sci 123, 331–334 (2011). https://doi.org/10.1007/s12039-011-0085-4
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DOI: https://doi.org/10.1007/s12039-011-0085-4