Abstract
Purpose
The authors sought to compare magnetic resonance imaging (MRI) and computed tomography (CT) for assessing left ventricular (LV) function parameters in a large patient population.
Materials and methods
The study was conducted on 181 patients who underwent cardiac MRI and cardiac CT for various indications. For MRI, we used two-dimensional cine balanced steady-state free precession (b-SSFP) sequences, and for CT we used multiphase short-axis reconstructions. Volume data sets were evaluated with dedicated software. Results were compared with a paired, two-tailed Student’s t test, Pearson’s correlation (r), and Bland-Altman analysis.
Results
A high level of concordance was observed between cardiac MRI and CT. Ejection fraction (EF) was 53±14% for MRI vs. 53%±15% for CT. There was good correlation for EF (r=0.71; p>0.05) and end-systolic volume (r=0.74; p>0.05). End-diastolic volume (74±23 ml at MRI vs. 71±19 ml at CT; r=0.58; p<0.05) and myocardial mass (63±20 g at MRI and 56±18 g at CT; r=0.89; p<0.01) showed statistically significant differences, although the discrepancy had no clinical impact.
Conclusions
MRI and CT show a good level of agreement in assessing LV function parameters, and both can be used interchangeably in clinical practice.
Riassunto
Obiettivo
Obiettivo di questo lavoro è stato confrontare la risonanza magnetica (RM) e la tomografia computerizzata (TC) per la valutazione dei parametri funzionali del ventricolo sinistro (Vsin) in una vasta popolazione di pazienti.
Materiali e metodi
Sono stati arruolati 181 pazienti che sono stati sottoposti ad esame cardio-RM e cardio-TC. Per la cardio-RM abbiamo utilizzato sequenze 2D cine b-steady-state free-precession (SSFP) e per la TC abbiamo utilizzato delle ricostruzioni multifasiche in asse corto. I data-set di volume sono stati analizzati con un software dedicato: Argus (versione Va60C). I risultati sono stati confrontati con il test t di Student a due code per dati appaiati, la correlazione di Pearson ed l’analisi di Bland-Altman.
Risultati
È stata osservata una elevata concordanza tra la cardio-RM e la cardio-TC. La frazione di eiezione (FE) è stata 53%±14% per la RM e 53%±15% per la TC. Buona correlazione è stata osservata per la FE (r=0,71; p>0,05) e per il volume tele-sistolico (VTS) (r=0,74; p>0,05). Il volume tele-diastolico (74±23 ml per RM e 71±19 ml per TC; r=0,58; p<0,05) e la massa miocardica (63±20 g per RM e 56±18 g per TC; r=0,89; p<0,01) hanno dimostrato differenze statisticamente significative anche se prive di impatto clinico.
Conclusioni
Gli esami cardio-RM e cardio-TC mostrano una eccellente concordanza per la valutazione dei parametri funzionali del Vsin e possono quindi essere utilizzati indifferentemente nella pratica clinica.
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Palumbo, A., Maffei, E., Martini, C. et al. Functional parameters of the left ventricle: comparison of cardiac MRI and cardiac CT in a large population. Radiol med 115, 702–713 (2010). https://doi.org/10.1007/s11547-010-0525-0
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DOI: https://doi.org/10.1007/s11547-010-0525-0
Keywords
- Cardiac magnetic resonance
- Cardiac computed tomography
- Left ventricular volumes
- Quantitative software
- Ejection fraction