We present here the results of studies of 34 patients aged 18–30 years with attention deficit hyperactivity disorder (ADHD) (ICD-10 F90.0). The form of ADHD with predominance of inattention was more frequent in adults (50% of patients), while the form with predominance of hyperactivity (11.7%) and the combined form (38.3%) were less common. The status of adult patients with ADHD was characterized by high levels of anxiety and asthenia. The efficacy and safety of Adaptol at a dose of 1500 mg/day for eight weeks were studied in the treatment of this group of patients. Clinical, psychological, and neurophysiological data demonstrated the high efficacy (improvements in 64.7% of cases) and safety of Adaptol.
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L. O. Badalyan, N. N. Zavadenko, and T. Yu. Uspenskaya, “Attention deficit disorder in children: A review,” Obozr. Psikh. Med. Psikhol. V. M. Bekhtereva, No. 3, 74–90 (1993).
I. P. Bryazgunov and E. V. Kasatikova, The Restless Child, or All About Hyperactive Children, Institute of Psychotherapy Press, Moscow (2001).
L. A. Gromov and E. T. Dudko, “‘Typical’ and ‘atypical’ tranquillizers,” Vestn. Farmakol. Farmatsii, No. 10, 11–17 (2003).
S. A. Zhivolupov, I. N. Samartsev, A. A. Marchenko, and O. V. Pulyatkina, “Prognostic significance of blood levels of brain-derived neurotrophic factor (BDNF) in the treatment of various functional and organic diseases of the nervous system using Adaptol,” Zh. Nevrol. Psikhiat, 112, No. 4, 37–41 (2012).
Z. Trzhesoglava, Mild Cerebral Dysfunction in Children, Meditsina, Moscow (1986).
P. Wender and R. Sheider, “Attention deficit hyperactivity disorder,” in Psychiatry [Russian translation], R. Sheider (ed.), Moscow (1998), pp. 222–236.
L. S. Chutko, A. B. Pal’chik, and Yu. D. Kropotov, Attention Deficit Hyperactivity Disorder, MAPO Press, St. Petersburg (2004).
L. S. Chutko, Attention Deficit Hyperactivity Disorder and Concomitant Disorders, Khoka, St. Petersburg (2007).
L. S. Chutko and S. Yu. Surushkina, “Clinical heterogeneity of attention deficit disorder,” Zh. Nevrol. Psikhiat., No. 8, 123–131 (2008).
R. A. Barkley, Attention Deficit Disorder with Hyperactivity: A Handbook for Diagnosis and Treatment, New York (1988).
R. A. Barkley, “Adolescents with attention-deficit/hyperactivity disorder: an overview of empirically based treatments,” J. Psych. Practice, No. 10, 39–56, (2004).
M. A. Bellgrove, Z. Hawi, M. Gill, and T. H. Robertson, “The cognitive genetics of attention deficit hyperactivity disorder (ADHD): sustained attention as a candidate phenotype,” Cortex, 42, No. 6, 838–845 (2006).
J. Biderman and S. Faraone, “Attention deficit hyperactivity disorder,” Lancet, 366, 237–248 (2005).
U. Ettinger, R. Joober, R. De Guzman, et al., “Schizotypy, attention deficit hyperactivity disorder, and dopamine genes,” Psychiatry Clin. Neurosci., 60, No. 6, 764–767 (2006).
S. Faraone, “What is the prevalence of adult ADHD? Results of a population screen of 966 adults,” Atten. Disord., 9, No. 2, 384–391 (2005).
S. V. Faraone and S. A. Khan, “Candidate gene studies of attentiondeficit/ hyperactivity disorder,” J. Clin. Psych., 67, Supplement 8, 13–20 (2006).
J. Fayyad, R. De Graaf, R. Kessler, et al., “Crossnational prevalence and correlates of adult attention-deficit hyperactivity disorder,” Brit. J. Psychiat., 190, 402 (2007).
M. Gill and G. Daly, “Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism,” Mol. Psychiatry, 2, No. 4, 464–468 (1997).
C. H. Kim, M. K. Hahn, Y. Joung, et al., “A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder,” Proc. Natl. Acad. Sci. USA, 103, No. 50, 19164–19169 (2006).
G. Polanczyk, M. S. de Lima, B. H. Horta, et al., “The worldwide prevalence of ADHD: a systematic review and metaregression analysis,” Am. J. Psychiat., 164, 942 (2007).
J. Sergeant, “The cognitive-energetic model: An empirical approach to attention-deficit hyperactivity disorder,” Neurosci. Biobehav. Rev., 24, 7–12 (2000).
D. B. Schatz and A. L. Rostain, “ADHD with comorbid anxiety: A review of the current literature,” J. Atten. Disord., 10, No. 2, 141–149 (2006).
M. L. Wolraich, “Addressing behavior problems among school-aged children: traditional and controversial approaches,” Pediatr. Rev., 18, No. 8, 266–270 (1997).
A. J. Zametkin and J. L. Rapoport, “Noradrenergic hypothesis of attention deficit disorder with hyperactivity: A critical review,” in: Psychopharmacology: The Third Generation of Progress H. V. Metsler (ed.), Raven, New York (1987), pp. 837–846.
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Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 113, No. 8, Iss. 1, pp. 38–41, August, 2013.
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Chutko, L.S., Surushkina, S.Y., Yakovenko, E.A. et al. Attention Deficit Disorder in Adults: Clinical and Psychophysiological Features and Treatment. Neurosci Behav Physi 44, 1078–1081 (2014). https://doi.org/10.1007/s11055-014-0028-x
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DOI: https://doi.org/10.1007/s11055-014-0028-x