Abstract
By regarding the circulation from the perspective of the venous return, continuous therapeutic control of the mean arterial blood pressure, cardiac output and tissue oxygen flow can be seen to be the consequence of a series of equations based on conventionally measured variables. This approach permits a graphical solution to circulation guidance, open or closed loop control and goal directed therapy of broad general applicability.
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References
Katz AM. Ernest Henry starling, his predecessors, and the “law of the heart”. Circulation 2002;106(23): 2986–2992.
Starling EH. The Linacre lecture on the law of the heart. London: Longmans, Green & Co.; 1918.
Lichtwarck-Aschoff M, Zeravik J, Pfeiffer UJ. Intrathoracic blood volume accurately reflects circulatory volume status in critically ill patients with mechanical ventilation. Intensive Care Med 1992;18(3):142–7.
Connors AF, Jr., Speroff T, Dawson NV, Thomas C, Harrell FE, Jr., Wagner D, Desbiens N, Goldman L, Wu AW, Califf RM, Fulkerson WJ, Jr., Vidaillet H, Broste S, Bellamy P, Lynn J, Knaus WA. The effectiveness of right heart catheterization in the initial care of critically ill patients. SUPPORT Investigators. JAMA. 1996 Sep 18;276(11):889–897.
Norton JM. Toward consistent definitions for preload and afterload. Adv Physiol Educ. 2001;25(1–4): 53–61.
Magder S. Clinical usefulness of respiratory variations in arterial pressure. Am J Respir Crit Care Med. 2004 Jan 15;169(2):151–155.
Michard F, Teboul JL. Predicting fluid responsiveness in ICU patients: a critical analysis of the evidence. Chest. 2002;121(6):2000–2008.
Pinsky MR. Rationale for cardiovascular monitoring. Curr Opin Crit Care. 2003;9(3):222–224.
Anderson RM. The gross physiology of the cardiovascular system. 2006; Available from: http://www.cardiovascular.cx/.
Guyton AC. Arterial pressure and hypertension. Philadelphia: Saunders; 1980.
London GM, Safar ME, Simon AC, Alexandre JM, Levenson JA, Weiss YA. Total effective compliance, cardiac output and fluid volumes in essential hypertension. Circulation. 1978;57(5):995–1000.
Guyton AC. Textbook of medical physiology. 7th ed. Philadelphia: Saunders; 1986.
Guyton AC, Lindsey AW, Kaufmann BN. Effect of mean circulatory filling pressure and other peripheral circulatory factors on cardiac output. Am J Physiol. 1955;180(3):463–468.
Maas JL, Van den Berg WK, Pinsky PC, Jansen MR, Jansen J. Venous return in ICU patients. Crit Care 2008;12(Suppl 2): P93
Parkin WG. Volume state control - a new approach. Crit Care Resusc. 1999;1(3):311–321.
Parkin G, Wright C, Bellomo R, Boyce N. Use of a mean systemic filling pressure analogue during the closed-loop control of fluid replacement in continuous hemodiafiltration. J Crit Care 1994;9(2):124–133.
Guyton AC. The surprising kidney-fluid mechanism for pressure control – its infinite gain! Hypertension. 1990;16(6): 725–730
Rose BD. Clinical physiology of acid-base and electrolyte disorders. 4th ed. New York: McGraw-Hill, Health Professions Division; 1994.
Keynes JM. The general theory of employment, interest and money. New York,: Harcourt, Brace; 1936.
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Parkin WG, Leaning MS. Therapeutic control of the circulation.
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Parkin, W.G., Leaning, M.S. Therapeutic control of the circulation. J Clin Monit Comput 22, 391–400 (2008). https://doi.org/10.1007/s10877-008-9147-7
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DOI: https://doi.org/10.1007/s10877-008-9147-7