Summary
We present a patient on enzyme replacement therapy who showed rapid deterioration when laronidase was discontinued owing to pregnancy.
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References
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Wraith JE, Clarke LA, Beck M, et al (2004) Enzyme replacement therapy for mucopolysaccharidosis I: a randomised, double-Blinded, placebo-controlled, multinational study of recombinant human α-L-iduronidase (laronidase). J Pediatr 144: 581–588.
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Communicating editor: Michael Gibson
Competing interests: None declared
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Anbu, A.T., Mercer, J. & Wraith, J.E. Effect of discontinuing of laronidase in a patient with mucopolysaccharidosis type I. J Inherit Metab Dis 29, 230–231 (2006). https://doi.org/10.1007/s10545-006-0237-8
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DOI: https://doi.org/10.1007/s10545-006-0237-8