We studied antiulcer activity of the extracts of ecdysteroid-containing plants of the Caryophyllaceae family: Lychnis chalcedonica L., Silene viridiflora L.Sp.Pl., and Silene frivaldszkyana Hampe. Experiments on the model of neurogenic and aspirin-induced ulcerogenesis showed unidirectional and pronounced gastroprotective effects of S. viridiflora and L. chalcedonica extracts comparable to the efficacy of famotidine. In these models, a course of intragastric treatment with the extracts reduced ulcerative lesions of all types.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 158, No. 8, pp. 190-194, August, 2014
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Krylova, S.G., Zueva, E.P., Zibareva, L.N. et al. Antiulcer Activity of Extracts of Ecdysteroid-Containing Plants of Genera Lychnis and Silene of the Caryophyllaceae Family. Bull Exp Biol Med 158, 225–228 (2014). https://doi.org/10.1007/s10517-014-2728-1
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DOI: https://doi.org/10.1007/s10517-014-2728-1