The volumes of foci of injuries, evaluated by T2-suspended MRT images and analysis of histological sections stained by triphenyltetrazoleum chloride, were compared on a model of unilateral intravascular blocking of the middle cerebral artery branch. The two methods for evaluation of foci of lesions gave close results, correlating with the severity of neurological deficiency in animals subjected to ischemia, manifesting in behavioral tests.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 147, No. 2, pp. 232–236, February, 2009
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Silachev, D.N., Uchevatkin, A.A., Pirogov, Y.A. et al. Comparative Evaluation of Two Methods for Studies of Experimental Focal Ischemia: Magnetic Resonance Tomography and Triphenyltetrazoleum Detection of Brain Injuries. Bull Exp Biol Med 147, 269–272 (2009). https://doi.org/10.1007/s10517-009-0489-z
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DOI: https://doi.org/10.1007/s10517-009-0489-z