Abstract
Apoptosis has been shown to be an efficient mechanism involved in clearance of T lymphocytes from the brains of animals with acute experimental autoimmune encephalomyelitis (EAE), an animal model for human multiple sclerosis. In this report we describe a case of acute disseminated encephalomyelitis following general measles infection. In this disease, which closely mimics the pathology of acute EAE we found a high percentage (30%) of apoptotic T cells. This indicates that in both rodent and human brain clearance of T cell-mediated inflammation follows similar mechanisms.
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Received: 17 December 1998 / Accepted: 11 January 1999
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Bauer, J., Stadelmann, C., Bancher, C. et al. Apoptosis of T lymphocytes in acute disseminated encephalomyelitis. Acta Neuropathol 97, 543–546 (1999). https://doi.org/10.1007/s004010051028
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DOI: https://doi.org/10.1007/s004010051028