Abstract
An unusual case of cerebellar neurocytoma with rhabdomyomatous differentiation in a 6-year-old boy is reported. Immunocytochemical and ultrastructural features of the tumour were studied. Abortive synapse formation, the presence of clear vesicles and synaptophysin immunoreactivity of the tumour cells indicated its intermediate neuronal differentiation, while the presence of myoblasts and myotubes and immunolabelling by desmin confirmed the rhabdomyomatous differentiation. In addition, the mesenchymal cells variably expressed neurofilament protein and glial fibrillary acidic protein, suggesting inductive interaction between the neuroectodermal and ectomesenchymal elements and persistence of the pleuripotential nature of the cells along the rhombic area of the brain stem.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
Author information
Authors and Affiliations
Additional information
Received: 3 June 1997 / Revised, accepted: 15 September 1997
Rights and permissions
About this article
Cite this article
Pal, L., Santosh, V., Gayathri, N. et al. Neurocytoma/rhabdomyoma (myoneurocytoma) of the cerebellum. Acta Neuropathol 95, 318–323 (1998). https://doi.org/10.1007/s004010050805
Issue Date:
DOI: https://doi.org/10.1007/s004010050805