Abstract
Despite sophisticated surgical methods only a few pediatric CNS tumors can be controlled by operation alone. Therefore multimodality treatment regimens are needed to improve quality of life and survival, which is most important in malignant neoplasms. Since 1998 we have treated 16 children with malignant CNS tumors. All 16 patients have been treated on an interdisciplinary basis and are therefore accompanied by a pediatric neuro-oncology group consisting of a neurosurgeon, pediatric oncologist, and radiotherapist. Depending on tumor histology, child"s age, and extent of surgery, further adjuvant therapy is planned by this group. Newly diagnosed tumors are typically treated by a specific chemotherapy protocol according to a multi-institutional study. In recurrent tumors more individual treatment regimens are considered. Data concerning surgery, adjunctive treatment, complications, and outcome of all patients and four case reports are presented.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
Author information
Authors and Affiliations
Additional information
Received: 3 January 2000
Rights and permissions
About this article
Cite this article
Messing-Jünger, A., Janssen, G., Pape, H. et al. Interdisciplinary treatment in pediatric patients with malignant CNS tumors. Child's Nerv Syst 16, 742–750 (2000). https://doi.org/10.1007/s003810000335
Issue Date:
DOI: https://doi.org/10.1007/s003810000335