Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans

Erratum to: Diabetologia

DOI 10.1007/s00125-007-0839-1

Unfortunately throughout the text of this Research Letter the labelling for the homozygous genotypes AA and CC was reversed, with the risk allele (A-allele) mistakenly being named C-allele and vice versa.

The affected sentences appear in corrected form below:

BMI was higher in carriers of the risk allele than in wild-type individuals (CC [n = 463] 27.2 ± 0.3 kg/m², CA[n = 732] 29.0 ± 0.3 kg/m², AA [n = 267] 29.5 ± 0.5 kg/m², mean ± SEM, p < 0.001) as a result of increased body weight (CC 79.8 ± 0.9 kg, CA 84.7 ± 1.0 kg, AA 84.8 ± 1.5 kg, p < 0.001).

Fig. 1a […] In subjects carrying the rare allele of rs8050136 in the homozygous or the heterozygous form (AA [n = 12] or AC [n = 18], BMI 27.3 ± 0.9 kg/m², mean ± SEM) the insulin effect on beta activity was significantly reduced compared with wild-type carriers (CC [n = 17], BMI 27.3 ± 1.2 kg/m²) (p = 0.016 by two-tailed Wilcoxon test). […]

In Fig. 1a the left column should be labelled CC and the right column CA/AA.