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Outcome predictors in the short-term treatment of anorexia nervosa: An integrated medical-psychiatric approach

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Abstract

Objectives: Factors predicting clinical outcome in the short-term treatment of anorexia nervosa. Design: Longitudinal follow-up study. Setting: Department of Clinical and Experimental Medicine, “Federico II” University of Naples. Participants: Fifty-eight young anorectic women consecutively attending the outpatient Unit between January 1997 and December 2000. Main outcome measures: Body weight changes over six months’ follow-up. Results: Body weight changes in the short term was exclusively predicted by the prevalent underlying psychiatric disorder, being increased in the patients with prevalently depressive traits, decreased in those with psychotic features and unchanged in those with a prevalently narcissistic personality. Conclusions: The prevalent psychiatric disorder seems to predict clinical outcome in the short term. Body weight gain per se cannot always be the main target of medical intervention, at least in the early phase of the treatment of malnutrition secondary to major eating disorders.

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References

  1. Fichter M.M., Quadflieg N.: Six-year course and outcome of anorexia nervosa. Int. J. Eat. Disord, 26, 359–385, 1999.

    Article  PubMed  CAS  Google Scholar 

  2. Herzog D.B., Dorer D.J., Keel P.K., Selwyn S.E., Ekeblad E.R., Flores A.T., Greenwood D.N., Burwell R.A., Keller M.B.: Recovery and relapse in anorexia nervosa and bulimia nervosa: a 7.5-year follow-up study. J. Am. Acad. Child Adolesc. Psychiatry, 38, 829–837, 1999.

    Article  PubMed  CAS  Google Scholar 

  3. Strober M., Freeman R., Morrell W.: The long term course of severe anorexia nervosa in adolescents: survival analysis of recovery, relapse and outcome predictors over 10-15 years in a prospective study. Int. J. Eat. Disord, 22, 339–360, 1997.

    Article  PubMed  CAS  Google Scholar 

  4. De Filippo E., Signorini A., Bracale R., Pasanisi F., Contaldo F.: Hospital admission and mortality rates in anorexia nervosa: experience from an integrated medical-psychiatric outpatient treatment. Eat. Weight Disord, 5, 211–216, 2000.

    PubMed  Google Scholar 

  5. Kohn M., Golden N.H.: Eating disorders in children and adolescents: epidemiology, diagnosis and treatment. Paediatr. Drugs, 3, 91–99, 2001.

    Article  PubMed  CAS  Google Scholar 

  6. Mehler P.S.: Diagnosis and care of patients with anorexia nervosa in primary care settings. Ann. Intern. Med., 134, 1048–1059, 2001.

    Article  PubMed  CAS  Google Scholar 

  7. American Psychiatric Association. Practice guideline for the treatment of patients with eating disorders (revision). Am. J. Psychiatry, 157 (1 suppl), 1–39, 2000.

    Google Scholar 

  8. Ben Tovim D.I., Walker K., Gilchrist P., Freeman R., Kalucy R., Esterman A.: Outcome in patients with eating disorders: a 5-year study. Lancet, 357, 1254–1257, 2001.

    Article  PubMed  CAS  Google Scholar 

  9. Fassino S., Abbate Daga G., Amianto F., Leombruni P., Fornas B., Garzaro L., D’Ambrosio G., Rovera G.G.: Outcome predictors in anorectic patients after 6 months of multimodal treatment. Psycother. Psychosom., 70, 201–208, 2001.

    Article  CAS  Google Scholar 

  10. Herzog W., Deter H.C., Fiehn W., Petzold E.: Medical findings and predictors of long-term physical outcome in anorexia nervosa: a prospective 12-year follow-up. Psyhcol. Med., 27, 269–279, 1997.

    CAS  Google Scholar 

  11. Bellini O., Scarnecchia M.: Il lavoro della cura nell’anoressia nervosa. Milano, F. Angeli, 2002.

    Google Scholar 

  12. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (text revision), Washington DC, APA, 2000.

  13. Cuzzolaro M.: Aut nimis aut nihil. Bulimia, anoressia e altri disturbi del comportamento alimentare. QUON, 1, 13–28, 1994.

    Google Scholar 

  14. Becker A.E., Griuspoan S.K., Herzoy D.B., Klifanski A.: Eating disorders. N. Engl. J. Med., 340, 1092–1098, 1999.

    Article  PubMed  CAS  Google Scholar 

  15. Sullivan P.F.: Mortality in anorexia nervosa. Am. J. Psychiatry, 152, 1073–1074, 1995.

    PubMed  CAS  Google Scholar 

  16. Moller-Madsen S.M., Nystrup J., Nielsen S.: Mortality of anorexia nervosa in Denmark 1970–1987. Ugeskr. Laeger., 160, 5509–5513, 1998.

    PubMed  CAS  Google Scholar 

  17. Neumarker K.J.: Mortality and sudden death in anorexia nervosa. Int. J. Eat. Dis., 21, 205–12, 1997.

    Article  CAS  Google Scholar 

  18. Zipfel S., Lowe B., Reas D.L., Deter H.C., Herzog W.: Long term prognosis in anorexia nervosa: lessons from a 21-year follow-up study. Lancet, 355, 721–722, 2000.

    Article  PubMed  CAS  Google Scholar 

  19. Herzog D.B., Nussbaum K.M., Marmor A.K.: Comorbidity and outcome in eating disorders. Psychiatr. Clin. North Am., 19, 843–859, 1996.

    Article  PubMed  CAS  Google Scholar 

  20. Saccomani L., Savoini M., Cirrincione M., Vercellino F., Ravera G.: Long term outcome of children and adolescents with anorexia nervosa: study of comorbidity. J. Psychosom. Res., 44, 565–571, 1998.

    Article  PubMed  CAS  Google Scholar 

  21. Sullivan H.S.: The psychiatric interview. New York, WW Norton & Company, 1954.

    Google Scholar 

  22. Palazzoli Selvini M.: L’anoressia mentale. Milano, Feltrinelli, 1963.

    Google Scholar 

  23. Bion W.R.: Transformations change from learning to growth. London, William Heinemann Medical books, 1965.

    Google Scholar 

Download references

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Correspondence to F. Contaldo M.D..

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Signorini, A., Bellini, O., Pasanisi, F. et al. Outcome predictors in the short-term treatment of anorexia nervosa: An integrated medical-psychiatric approach. Eat Weight Disord 8, 168–172 (2003). https://doi.org/10.1007/BF03325008

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