Summary
A comparative evaluation has been made of the effects of different anaesthetic agents and techniques upon the mortality of patients undergoing intracranial surgery for ruptured intracranial aneurysms. No statistically significant difference was noted when comparing groups in which halothane or trichlorethylene was the main anaesthetic agent. Neither was there any difference in mortality in groups in which halothane was used with or without controlled ventilation. It is concluded that variation in agent or method of general anaesthesia, which should on theoretical grounds result in differences in cerebral blood flow, has not affected postoperative mortality rates either adversely or beneficially.
Résumé
On a fait une étude comparée de l’effet de différents agents et techniques anesthésiques sur la mortalité de malades opérés pour rupture d’anévrysmes intra-crâniens. On n’a pas noté de différences sensibles dans les groupes où l’halothane ou le trichloréthylène étaient utilisés comme agent anesthésique principal. On n’a pas non plus trouvé de différence de mortalité, que l’halothane aît été utilisé avec ou sans ventilation contrôlée. En conclusion, le changement d’agent ou de technique, qui théoriquement devrait faire varier la circulation cérébrale, n’a pas influencé le taux de mortalité post-opératoire, ni en plus ni en moins.
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Marshall, B.M., Lougheed, W.M. & Gordon, R.A. Evaluation of the effect of anaesthetic techniques on survival after intracranial surgery for ruptured aneurysms. Can. Anaesth. Soc. J. 15, 227–231 (1968). https://doi.org/10.1007/BF03008735
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DOI: https://doi.org/10.1007/BF03008735