Summary
Thirteen patients were studied during two hours of anaesthesia for abdominal operations and for an hour post-operatively. Serial venous blood samples were taken for determination of plasma total and ionized calcium, acid-base variables, Na, K, Mg, PO4 total proteins and parathyroid hormone. One group of patients received 5 per cent dextrose/water and the other 5 per cent dextrose in Ringer’s solution, at 250 ml per hour. Total and ionized calcium levels decreased toward the end of operation and an hour later, associated with respiratory alkalosis. Parathyroid hormone increased at the end of operation, as an effect of the decreased ionized calcium. The general effect was mild haemodilution with all the other electrolytes decreasing, as did total protein concentration.
Résumé
Des prélèvements veineux ont été faits chez 13 opérvs durant des anesthésies d’une durée de 2 heures et ont été répétés durant la première heure postopératoire. Les paramètres étudiés ont été le calcium total et le calcium ionisé, l’equilibre acido-basique, le sodium, le potassium, le magnésium et les phosphates, les protvines totales et la parathormone. Un groupe de patients a reçu du dextrose à 5 pour cent dans l’eau et l’autre groupe a regu une solution de dextrose à 3 pour cent dans le Ringer, à raison de 250 ml à l’heure.
Les taux de calcium total et ionisés étaient diminués vers la fin de l’intervention et dans l’heure suivant l’intervention, ceci associé avec une alcalose respiratoire. Les taux de parathormone s’élevaient en fin d’intervention, un effet lié à la diminution du calcium ionisé. Quant aux autres électrolytes et aux protéines totales, leurs taux reflétaient une hémodilution légere.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Williams, R.J.P. &Wacker, W.E.C. Cation balance in biological systems. J.A.M.A.201: 96 (1967).
Entman, M.L. Calcium and cardiac contractility. Amer. J. Med. Sciences259: 164 (1970).
Moore, E.W. Ionized calcium in normal serum, ultrafiltrar.es, and whole blood determined by ion-exchange electrodes. J. Clin. Invest.49: 318 (1970).
Arnaud, CD., Tsao, H.S., &Littledike, T. Radioimmunoassay of human parathyroid hormone in serum. J. Clin. Invest.50: 21 (1971).
Kaplan, E.L., Hill, B.J., Locke, S., &Peskin, G.W. Acid-base balance and parathyroid function: metabolic alkalosis and hyperparathyroidism. Surgery70: 198 (1971).
Hinkle, J.E. &Cooperman, L.H. Serum ionized calcium changes following citrated blood transfusion in anaesthetized man. Br. J. Anaes.43: 1108 (1971).
Das, J.B., Eraklis, A.J., Adams, J.G., Jr., &Gross, R.E. Changes in serum ionic calcium during cardiopulmonary bypass with hemodilution. J. Thorac. Cardiovasc. Surg.62: 449 (1971).
Killen, D.A., Grogan, E.L., II Gower, R.E., Collins, I.S., &Collins, H.A. Effect of ACD blood prime on plasma calcium and magnesium. Ann. Thorac. Surg.13: 371 (1972).
Johnson, A.E., Radde, I.C., Nisbet, H.I.A., &Taylor, U. Effects of altering calcium in haemodiluted pump primes on sodium and potassium in children undergoing open-heart operations. Can. Anaesth. Soc. J.19: 517 (1972).
Moffitt, E.A., Tarhan, S., Goldsmith, R.S., Pluth, J.R., &McGoon, D.C. Patterns of total and ionized calcium and other electrolytes in plasma during and after cardiac surgery. J. Thorac. Cardiovasc. Surg.65: 751 (1973).
Nisbet, H.I.A., Mathur, A.K., Dobbinson, T.L., Steward, D.J., & Volgyesi, G.A. The effect of artificial ventilation on FRC and arterial oxygenation. 3. Low and normal arterial carbon dioxide tension during ventilation with sine wave and inspiratory hold patterns. Canad. Anaesth. Soc. J. In Press.
Moffitt, E.A., Schnelle, N., Rodriguez, R., Lee, R.A., &Judd, E.S. Effects of intra- venously administered solutions on electrolytes and energy substrates during surgery. Canad. Anaesth. Soc. J.21: 285 (1974).
Author information
Authors and Affiliations
Additional information
This work was supported in part by grant GM 14919 from the National Institutes of Health, Public Health Service.
Rights and permissions
About this article
Cite this article
Rodriguez, R., Jones, R.R., Adson, M.A. et al. Patterns of total and ionized calcium and other electrolytes in plasma during and after general surgery. Canad. Anaesth. Soc. J. 23, 15–21 (1976). https://doi.org/10.1007/BF03004990
Issue Date:
DOI: https://doi.org/10.1007/BF03004990