Summary and Conclusions
One hundred and forty-four patients with massive hemorrhages resulting from gastric or duodenal ulcer were treated by the continuous administration of colloidal aluminum hydroxide. In this series, there were three deaths, or a mortality rate of 2 per cent, as contrasted to a mortality rate of 28 per cent during a similar period at the same hospital, preceding the inauguration of this form of medical treatment. The continuous administration of colloidal aluminum hydroxide in massive gastric hemorrhage presents certain advantages over other methods of treatment:
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1.
It is a harmless, non-absorbable astringent which is capable of hastening the formation of a clot.
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2.
By virtue of its antacid properties it can prevent the digestion of the clot by continuously neutralizing the excess acid in the stomach, without danger of alkalosis.
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3.
Because it is a gelatinous substance, it has the additional advantage of mechanically protecting the lesion.
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4.
As the result of continuous administration of colloidal aluminum hydroxide, both day and night, the delicate granulation tissue formed in the process of healing is not destroyed by the accumulation of acid during the night, and thus the lesion is permitted to heal.
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References
Rivers, A. B. and Wilbur, D. L.: Intrinsic Gastro-Duodenal Lesions as Causative Factors of Hematemesis.Arch. Int. Med., 50:621–634, Oct., 1932.
Blackford, J. M. and Cole, W. S.: Massive Hemorrhage from Peptic Ulcer. A study based on vital statistics of the city of Seattle.Am. J. Dig. Dis., 6:637–640, Nov., 1939.
Christiansen, Tage: On Massive Hemorrhage in Peptic Ulcers.Acta Med. Scandinav., 84:374–385, 1935.
Andresen, A. F. R.: Treatment of Gastric Hemorrhage.J. A. M. A., 89:1397–1400, Oct. 22, 1927.
Meulengracht, E.: The Treatment of Hematemesis and Melena with Food.Lancet, 2:1220, Nov. 30, 1935.
Woldman, E. E. and Rowland, V. C.: A New Technique for the Continuous Control of Acidity in Peptic Ulcer by Aluminum Hydroxide Drip.Am. J. Dig. Dis. and Nutrit., 2:733–736, Feb., 1936.
Woldman, E. E.: The Treatment of Hematemesis and Melena by a Continuous Aluminum Hydroxide Drip.Am. J. Med. Sci, 194:333–340, Sept., 1937.
Woldman, E. E. and Polan, C. H.: Value of Colloidal Aluminum Hvdroxide in the Treatment of Peptic Ulcer.Am. J. Med. Sci., 198:155–164, Aug., 1939.
Woldman, E. E.: A Collapsible Indwelling Nasogastric TubeAm. J. Dig. Dis. and Nutrit., 4:428–429, Sept., 1937.
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Woldman, E.E. The treatment of massive gastro-duodenal hemorrhage by the continuous administration of colloidal aluminum hydroxide (A Report of 144 Cases). Jour. D. D. 8, 39–42 (1941). https://doi.org/10.1007/BF03000039
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DOI: https://doi.org/10.1007/BF03000039