Abstract
For comparing with flavones/flavonols, isoflavonoids isolated fromPueraria radix and chemically synthesized from biochanin A were evaluated for the antiinflammatory activity using mouse ear edema test. Isoflavonoids such as daidzein and puerarin showed the significant antiinflammatory activity at a dose of 2 mg/mouse, although their activity was generally less than that of flavones/flavonols. 7-O-Substitution of biochanin A was not favorable for the antiinflammatory activity.
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Lee, S.J., Baek, H.J., Lee, C.H. et al. Antiinflammatory activity of isoflavonoids fromPueraria radix and biochanin A derivatives. Arch. Pharm. Res. 17, 31–35 (1994). https://doi.org/10.1007/BF02978244
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DOI: https://doi.org/10.1007/BF02978244