Abstract
Five furanocoumarins including a new one were isolated from the root ofAngelica dahurica by repeated silica gel column chromatography. Their chemical structures were determined to be isoimperatorin (1), oxypeucedanin hydrate-3″-butyl ether (2), imperatorin (3), knidilin (4), and oxypeucedanin hydrate (5). This represents the first study in which the compound2 has been isolated and identified. The long-range coupling (5 J) in the1H-NMR spectrum observed in the linear furanocoumarin skeleton was also investigated in detail.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Baek, N. I., Ahn, E. M., Han, J. T., Park, J. K., Cho, S. W., Jeon, S. G., Bahn, J. H., Sun, H. J. and Choi, S. Y., Effects of Several Medicinal plants on Activity of GABA-metaboliting Enzymes.Kor. J. Pharmacogn., 31, 23–27 (2000).
Gu, Z. M., Zhang, D. X., Yang, X. W., Hattori, M. and Namba, T., Isolation of Two New Coumarin Glycosides fromNotopterygium forbesii and Evaluation of a Chinese Crude Drug, Qiang-Huo, the Underground Parts ofN. incisum andN. forbesii, by High-Performance Liquid Chromatography.Chem. Pharm. Bull., 38, 2498–2502 (1990).
Hata, K., Nishino, T., Hirai, Y., Wada, Y. and Kozawa, M., On Coumarins from the Fruits ofAngelica pubescens Maxim.Yakugaku zasshi, 101, 67–71 (1981).
Harkar, S., Razdan, T. K. and Waight, E. S., Steroids chromone and coumarins fromAngelica officinalis.Phytochemistry, 23, 419–426 (1984).
Kim, S. H., Kang, S. S. and Kim, C. M., Coumarin Glycosides from the Roots ofAngelica dahurica.Arch. Pharm. Res., 15, 73–77 (1992).
Kozawa, M., Baba, K., Okuda, K., Fukumoto, T. and Hata, K., Studies on Chemical Components of “Bai zhi” On Coumarins from “Japanese Bai Zhi”.Shoyakugaku Zasshi, 35, 90–95 (1981).
Lee, C. K. and Woo, W. S., Coumarin Constituents from the Roots ofAngelica Koreana Max.Kor. J. Pharmacogn., 13, 10–13 (1982).
Pavia, D. L., Lampman, G. M. and Kriz, G. S.,Introduction to spectroscopy. 2nd Ed., Saunders College Press, Florida, pp. 203–204, (1996).
Qiao, S. Y., Yao, X. S. and Wang, Z. Y., Coumarins of the Roots ofAngelica dahurica.Planta Med., 62, 584 (1996).
Sasaki, H., Taguchi, H., Endo, T. and Yosioka, I., The Constituents ofLedebouriella seseloides Wolff. I. Structures of Three New Chromones.Chem. Pharm. Bull., 30, 3555–3562 (1982).
Shin, K. H., Moon, K. H. and Woo, W. S., Two Minor Furanocoumarins ofAngelica dahurica.Arch. Pharm. Res., 14, 165–166 (1991).
Soka, T.,Dictionary of Chinese Drugs. Shanghai Science Technology Shogakukan (Eds.) Shogakuhan Press, Tokyo, pp. 2243–2246 (1985).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Baek, N.I., Ahn, E.M., Kim, H.Y. et al. Furanocoumarins from the root ofAngelica dahurica . Arch Pharm Res 23, 467–470 (2000). https://doi.org/10.1007/BF02976574
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02976574