Summary
A case of botryoid sarcoma of the common bile duct in a 4-year-old girl was reported. Electron microscopic examination disclosed that the neoplasm consisted of three types of cells: polygonal, elongated, and small cells. The former two contained moderate to large amounts of poorly developed myofibriles in the cytoplasm with occasional A, I and Z-bands. The small cells contained mitochondria and dilated rough endoplasmic reticulum but few myofilaments. Deposits of glycogen granules were constant components of the neoplastic cells. Mitosis was striking in the small cells. Abnormal multilaminar endoplasmic reticulum was observed in the small cells in the mitotic stage.
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Bergman RA: Observation on the morphologenesis of rat skeletal muscle. Bull Johns Hopkins Hosp 110: 187, 1962
Bloom W, Fawcett DW: A textbook of histology, Tenth edition, p. 295. W.B. Saunders Company, Philadelphia, London, Toronto, 1975
Chapman GB, Jones IS, Spelberg WW: An electron microscope study of rhabdomyosarcoma. Invest Ophthal 2: 538, 1967
Corbeil LB: Differentiations of rhabdomyosarcoma and neonatal muscle cells in vitro. Cancer 20: 572, 1966
Delany MH, Driscoll PJ, Ainsworth H: Sarcoma botryoides of the common bile duct. J Pediat Surg 1: 571, 1966
Ebihara Y, Kitazawa Y, Shoda H, Koya N, Shike S: An autopsy case of embryonal rhabdomyosarcoma, light and electron microscopic observations. J Clin Electron Microscopy 7: 177, 1974
Fishman DA: An electron microscope study of myofibril formation in embryonal chick skeletal muscle. J Cell Biol 32: 557, 1967
Friedman E, Harrison DFN, Tucker WN, Bird ES: Electron microscopy of rhabdomyosarcoma of the ear. J Clin Path 18: 63, 1965
Hays DM, Snyder WH Jr`: Botryoid sarcoma of the bile ducts. Amer J Dis Child 110: 595, 1965
Horn RC, Yokovac WC, Kaye R, Koop CE: Rhabdomyosarcoma of the common bile duct. Cancer 8: 468, 1955
Horvat BL, Caines M, Fisher ER: The ultrastructure of rhabdomyosarcoma. Am J Clin Path 53: 55, 1970
Imaizumi M, Nukada T, Okada F, Abe H: Fine structure of rhabdomyosarcoma. J Electron Micro 23: 124, 1974
Kroll AJ, Kuwabara T, Howard GM: Electron microscopy of rhabdomyosarcoma of the orbit. Invest Ophthal 2: 523, 1963
Parmley RT, Spicer SS, Garvin AJ: Multilaminar endoplasmic reticulum and abnormal mitosis in Hodgkin tumor cells. Cancer Res 36: 1717, 1968
Rhodin JAG: Histology, a text and atlas, p 221. New York, Oxford University Press, London, Toronto, 1974
Sarber K, Tomnai G, McKay DE: Embryonal rhabdomyosarcoma of the prostate. Cancer31: 442, 1972
Soper RT, Dunphy DL: Sarcoma botryoides of the biliary tree. Surgery 63: 1005, 1968
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Taura, S., Taura, M., Tanaka, N. et al. Ultrastructure of botryoid sarcoma of the common bile duct. Gastroenterol Jpn 12, 305–310 (1977). https://doi.org/10.1007/BF02776799
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DOI: https://doi.org/10.1007/BF02776799