Abstract
Three keratoplasties were carried out on two patients because of nodular degeneration of the cornea. Progress after keratoplasty could be followed up in one eye for 17 months and in the other two eyes, for 2.5 and 9 years, respectively. The implant with the short follow-up of only 17 months remained glass-clear; nothing abnormal was discovered during the checkups. In the case of the other patient in whom a longer follow-up period was possible, the following findings were evident: (1) a remarkably late epithelial immune response in one eye (after 18 months) with subsequent incomplete reepithelisation and formation of fine, superficial, cloudy opacity (observation period 2.5 years); (2) formation of dense but flat, superficial areas of opacity in the cornea of the other eye (observation period 9 years). These areas may be regarded as a precursor of Salzmann’s corneal degeneration. No difference could be found between the histological findings in the explants and those in a degenerative pannus or an older scar caused by inflammation of the Bowman membrane.
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References
Alexander RA, Garner A (1981) Oxytalan fibre formation in the cornea: a light and electron microscopical study. Histopathology 1:189–199
Alexander RA, Grierson I, Garner A (1981) Oxytalan fibres in Fuchs’ endothelial dystrophy. Arch Ophthalmol 99:1622–1627
Bischler V (1946) Dystrophie cornéene nodulaire de Salzmann. Ophthalmologica 3:111–119
Fullmer HM, Lillie RD (1958) The oxytalan fibres: a previously undescribed connective tissue fibre. J Histochem Cytochem 6:425–430
Houber JP (1970) Récidive bilaterale d’une dégénérescence nudulaire de Salzmann après greffe perforante de la cornée. Ophthalmology 161:90–97
Muir EB (1940) Salzmann’s nodular corneal dystrophy. Am J Ophthalmol 23:138–141
Pau H, Schmitt-Gräff A (1982) Salzmann’sche Hornhautdystrophie. Graefe’s Arch Clin Exp Ophthalmol 218:161–167
Rodrigues MM, Simjee A, Laibson PR, Weinreb S (1979) Salzmann’s nodular degeneration of the cornea: a clinicopathologic study. Metab Pediatr Syst Ophthalmol 3:41–46
Salzmann M (1925) Über eine Abart der knötchenförmigen Hornhautdystrophie. Z Augenheilkd 57:92–99
Severin M (1986) Immunreaktion nach Keratoplastik. Klin Montasbl Augenheilkd 188:200–208
Vannas A, Hogan MJ, Wood I (1975) Salzmann’s nodular degeneration of the cornea. Am J Ophthalmol 79:211–219
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Severin, M., Kirchhof, B. Recurrent salzmann’s corneal degeneration. Graefe’s Arch Clin Exp Ophthalmol 228, 101–104 (1990). https://doi.org/10.1007/BF02764300
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DOI: https://doi.org/10.1007/BF02764300