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Wolfram syndrome

Case report and review of the literature

  • Case Report
  • Published:
Annals of Ophthalmology

Abstract

Wolfram syndrome (WFS) is a rare diffuse neurodegenerative disorder characterized by diabetes insipidus, diabetes mellitus, optic atrophy, deafness, and a wide variety of central nervous system abnormalities. Insulin-dependent diabetes mellitus with optic nerve atrophy is sufficient criteria for the diagnosis. WFS is a devastating disease for the patients and their families. This study emphasizes the need for careful evaluation of cases having insulin-dependent diabetes mellitus and optic atrophy.

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Author information

Authors and Affiliations

  1. Department of Opthalmology, Diyarbakir State Hospital, Diyarbakir, Turkey

    Şeyhmus Ari MD

  2. Department of Opthalmology, Dicle University Faculty of Medicine, Diyarbakir, Turkey

    Uğur Keklíkçí MD (Assistant Professor), Ihsan Çaça MD (Associate Professor) & Kaan Ünlü MD (Professor)

  3. Department of Internal Medicine, Dicle University Faculty of Medicine, Diyabakir, Turkey

    Hasan Kayabaşi MD

Authors
  1. Şeyhmus Ari MD
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  2. Uğur Keklíkçí MD
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  3. Ihsan Çaça MD
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  4. Kaan Ünlü MD
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  5. Hasan Kayabaşi MD
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Corresponding author

Correspondence to Şeyhmus Ari MD.

Additional information

The authors have stated that they do not have a significant financial interest or other relationship with any product manufacturer or provider of services discussed in this article. The authors also do not discuss the use of off-labed products, which includes unlabeled, unapproved, or investigative products or devices.

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Ari, Ş., Keklíkçí, U., Çaça, I. et al. Wolfram syndrome. Ann Ophthalmol 39, 53–55 (2007). https://doi.org/10.1007/BF02697327

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  • DOI: https://doi.org/10.1007/BF02697327

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