Abstract
The experimental design in examination of acute myocardial infarctions should be valid in terms of flow, perfusion and re-flow after intervention. The contrast agents concentration in experimental studies can be measured by microdialysis. We have assessed the usefulness of different extracellular and blood pool contrast agents for visualization of the area at risk in coronary artery occlusions. The double contrast technique, where Dy-DTPA-BMA was combined with Gd-DTPA-BMA yielded a superior infarct visualization. Blood pool agents for example NC100/150 injection is also promising in first path myocardial perfusion imaging.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Bjerner T. Johansson LO, Bjørnerud A, Ahlström H. Hemmingsson A. High Resolution T2-weighted First-Pass Myocardial Perfusion Imaging using Outer-Volume Suppression and the Intravascular Contrast Agent NC100150 Injection. ISM RM, Denver 2000.
Bjerner T. Johansson LO. Bjørnerud A, Wikström G, Ahlström H. Hemmingsson A. High Resolution T2-weighted Steady State Myocardial Perfusion Imaging using the Intravascular Contrast Agent NC100150 Injection. ISMRM Denver 2000.
Bjerner T. Johansson LO, Bjørnerud A, Wikström G, Ahlström H. Hemmingsson A, High-Resolution T2-weighted First-Pass Myocardial Perfusion Imaging using Outer-Volume Suppression and the Intravascular Contrast Agent NC100150 Injection. ISMRM Denver 2000.
Gruppo Italiano Perlo Studo Delia Streptochinasi Nell Infart Miocardico (GISSI): Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet 1 (1986). 397.
Hjalmarsson A. Elmfeldt D, Herlitz J, et al. Effect on mortality of metoprolol in acute myocardial infarction. A double-blind randomised trial. Lancet 1981;2:823.
ISIS-2 (Second International Study of Infarct Survival) Collaborative Group.: Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17 187 cases of suspected acute myocardial infarction. Lancet 2 (1988), 349.
Nilsson S. MR imaging of Contrast-Enhanced Porcine Myocardial Infarction. Assessment of reperfusion and tissue viability, Acta Radiol. 36 (1995) Suppl. 397. p. 45.
Wikström M, Magnetic Resonance Imaging of Experimental Myocardial Infarction. Acta Radiol. 33 (1992). Suppl. 379, p. 30.
Wilcox RG, Vonderlippe G, Olsson CG, Jensen G, Skene AM, Hampton JR. Trial of tissue plasminogen activator for mortality reduction in acute myocardial infarction. Lancet 1988;2:525.
Zijlstra F, Boer MJD, Hoorntje JCA, Reiffers S, Reiber JHC, Suryapranata H. A comparison of immediate coronary angioplasty with intravenous streptokinase in acute myocardial infarction. New Engl J Med 1993:11:680.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Hemmingsson, A., Bjerner, T., Ericsson, A. et al. Contrast agents in acute myocardial infarction. MAGMA 12, 96–98 (2001). https://doi.org/10.1007/BF02668089
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02668089