Abstract
A polarographic technique using flush mounted electrodes in the wall of a tube was used to measure augmentation of diffusion in flowing suspensions of bovine red blood cells in a region close to the tube wall. The effective diffusion coefficient was found to be an increasing function of particle Peclet number (based on the wall shear rate) and volume fraction of cells. Comparison of these results with experimentally measured diffusion augmentation in a system where wall effects were negligible provides information on the behavior of the cell-free skimming layer at the tube wall. The thickness of this skimming layer is dependent on the wall shear rate and on the bulk hematocrit. Below hematocrits of 25% the skimming layer thickness decreases with increasing wall shear rate, while above 25% hematocrit the skimming layer becomes thicker as the wall shear rate increases.
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References
Bugliarello, G. and J. Sevilla Velocity distribution and other characteristics of steady and pulsatile blood flow in fine glass tubes.Biorheology 7:85–107, 1970.
Collingham, R.E. Mass transfer in flowing suspensions. Ph.D. thesis, University of Minnesota, Minneapolis, MN, 1968.
Fricke, H. A mathematical treatment of the electric conductivity and capacity of disperse systems. I The electric conductivity of a suspension of hemogeneous spheroids.Phys. Rev. 24:575–587, 1924.
Goldsmith, H.L. and J.C. Marlow. Flow behavior of erythrocytes. II. Particle motions in concentrated suspensions of ghost cells.J. Coll. Interface Sci. 71:383–407, 1979.
Keller, K.H. Mass transport phenomena in biological systems. In:Bio-materials, edited by Starke and Agarwal. New York: Plenum Press, 1969.
Keller, K.H. Effect of fluid shear on mass transport in flowing blood.Fed. Proc. 30:1591–1599, 1971.
Lutz, R.J., J. N. Cannon, K. B. Bischoff, R. L. Dedrick, R. K. Stiles, and D. L. Fry. Wall shear stress distribution in a model canine artery during steady flow.Circ. Res. 41:391–399, 1977.
Petschek, H.E. and R. F. Weiss. Hydrodynamic problems in blood coagulation. AIAA paper 70-143, AIAA 3rd Fluid and Plasma Dynamics Conference, Los Angeles, 1970.
Reiss, L.P. and T. J. Hanratty. Measurement of instantaneous rates of mass transfer to a small sink on a wall.AICHE J. 8: 245–247, 1962.
Schwartz, A. J. Mass transport in flowing blood. Ph.D. thesis, University of Minnesota, Minneapolis, MN, 1979.
Wang, N.H.L. Effects of fluid shear on the mass transport properties of erythrocyte suspensions. Ph.D. thesis, University of Minnesota, Minneapolis, MN, 1978.
Wang, N.H.L. and K. H. Keller. Solute transport induced by erythrocyte motions in shear flow.Trans. Am. Soc. Artif. Intern. Organs, 25: 14–18, 1979.
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Schwartz, A.J. Mass transport in flowing blood: Augmentation of solute transport near the wall of a circular conduit. Ann Biomed Eng 8, 197–207 (1980). https://doi.org/10.1007/BF02364476
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DOI: https://doi.org/10.1007/BF02364476